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Shear Stress in Schlemm’s Canal as a Sensor of Intraocular Pressure

Elevated intraocular pressure (IOP) narrows Schlemm’s canal (SC), theoretically increasing luminal shear stress. Using engineered adenoviruses containing a functional fragment of the shear-responsive endothelial nitric oxide synthase (eNOS) promoter, we tested effects of shear stress and elevated fl...

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Detalles Bibliográficos
Autores principales:	McDonnell, Fiona, Perkumas, Kristin M., Ashpole, Nicole E., Kalnitsky, Joan, Sherwood, Joseph M., Overby, Darryl R., Stamer, W. Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118084/ https://www.ncbi.nlm.nih.gov/pubmed/32242066 http://dx.doi.org/10.1038/s41598-020-62730-4

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