A novel silicone derivative of natural osalmid (DCZ0858) induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma via the JAK2/STAT3 pathway

Diffuse large B-cell lymphoma (DLBCL) is a highly heterogeneous malignant tumor characterized by diffuse growth. DCZ0858 is a novel small molecule with excellent antitumor effects in DLBCL. This study explored in depth the inhibitory effect of DCZ0858 on DLBCL cell lines. Cell Counting Kit-8 (CCK-8)...

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Detalles Bibliográficos
Autores principales: Lu, Kang, Li, Bo, Zhang, Hui, Xu, Zhijian, Song, Dongliang, Gao, Lu, Sun, Haiguo, Li, Liping, Wang, Yingcong, Feng, Qilin, Chen, Gege, Hu, Liangning, Wei, Rong, Xie, Yongsheng, Yu, Dandan, Wu, Xiaosong, Zhu, Weiliang, Shi, Jumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118088/
https://www.ncbi.nlm.nih.gov/pubmed/32296013
http://dx.doi.org/10.1038/s41392-020-0123-0

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