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ASK1 inhibits browning of white adipose tissue in obesity
Increasing energy expenditure via induction of adipose tissue browning has become an appealing strategy to treat obesity and associated metabolic complications. Herein, we identify adipocyte-expressed apoptosis signal-regulating kinase 1 (ASK1) as regulator of adipose tissue browning. High fat diet-...
Autores principales: | Lucchini, Fabrizio C., Wueest, Stephan, Challa, Tenagne D., Item, Flurin, Modica, Salvatore, Borsigova, Marcela, Haim, Yulia, Wolfrum, Christian, Rudich, Assaf, Konrad, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118089/ https://www.ncbi.nlm.nih.gov/pubmed/32242025 http://dx.doi.org/10.1038/s41467-020-15483-7 |
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