A salvage pathway maintains highly functional respiratory complex I

Regulation of the turnover of complex I (CI), the largest mitochondrial respiratory chain complex, remains enigmatic despite huge advancement in understanding its structure and the assembly. Here, we report that the NADH-oxidizing N-module of CI is turned over at a higher rate and largely independen...

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Detalles Bibliográficos
Autores principales: Szczepanowska, Karolina, Senft, Katharina, Heidler, Juliana, Herholz, Marija, Kukat, Alexandra, Höhne, Michaela Nicole, Hofsetz, Eduard, Becker, Christina, Kaspar, Sophie, Giese, Heiko, Zwicker, Klaus, Guerrero-Castillo, Sergio, Baumann, Linda, Kauppila, Johanna, Rumyantseva, Anastasia, Müller, Stefan, Frese, Christian K., Brandt, Ulrich, Riemer, Jan, Wittig, Ilka, Trifunovic, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118099/
https://www.ncbi.nlm.nih.gov/pubmed/32242014
http://dx.doi.org/10.1038/s41467-020-15467-7

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