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Integrated Optofluidic Chip for Oscillatory Microrheology

We propose and demonstrate an on-chip optofluidic device allowing active oscillatory microrheological measurements with sub-μL sample volume, low cost and high flexibility. Thanks to the use of this optofluidic microrheometer it is possible to measure the viscoelastic properties of complex fluids in...

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Autores principales: Vitali, Valerio, Nava, Giovanni, Zanchetta, Giuliano, Bragheri, Francesca, Crespi, Andrea, Osellame, Roberto, Bellini, Tommaso, Cristiani, Ilaria, Minzioni, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118116/
https://www.ncbi.nlm.nih.gov/pubmed/32242060
http://dx.doi.org/10.1038/s41598-020-62628-1
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author Vitali, Valerio
Nava, Giovanni
Zanchetta, Giuliano
Bragheri, Francesca
Crespi, Andrea
Osellame, Roberto
Bellini, Tommaso
Cristiani, Ilaria
Minzioni, Paolo
author_facet Vitali, Valerio
Nava, Giovanni
Zanchetta, Giuliano
Bragheri, Francesca
Crespi, Andrea
Osellame, Roberto
Bellini, Tommaso
Cristiani, Ilaria
Minzioni, Paolo
author_sort Vitali, Valerio
collection PubMed
description We propose and demonstrate an on-chip optofluidic device allowing active oscillatory microrheological measurements with sub-μL sample volume, low cost and high flexibility. Thanks to the use of this optofluidic microrheometer it is possible to measure the viscoelastic properties of complex fluids in the frequency range 0.01–10 Hz at different temperatures. The system is based on the optical forces exerted on a microbead by two counterpropagating infrared laser beams. The core elements of the optical part, integrated waveguides and an optical modulator, are fabricated by fs-laser writing on a glass substrate. The system performance is validated by measuring viscoelastic solutions of aqueous worm-like micelles composed by Cetylpyridinium Chloride (CPyCl) and Sodium Salicylate (NaSal).
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spelling pubmed-71181162020-04-08 Integrated Optofluidic Chip for Oscillatory Microrheology Vitali, Valerio Nava, Giovanni Zanchetta, Giuliano Bragheri, Francesca Crespi, Andrea Osellame, Roberto Bellini, Tommaso Cristiani, Ilaria Minzioni, Paolo Sci Rep Article We propose and demonstrate an on-chip optofluidic device allowing active oscillatory microrheological measurements with sub-μL sample volume, low cost and high flexibility. Thanks to the use of this optofluidic microrheometer it is possible to measure the viscoelastic properties of complex fluids in the frequency range 0.01–10 Hz at different temperatures. The system is based on the optical forces exerted on a microbead by two counterpropagating infrared laser beams. The core elements of the optical part, integrated waveguides and an optical modulator, are fabricated by fs-laser writing on a glass substrate. The system performance is validated by measuring viscoelastic solutions of aqueous worm-like micelles composed by Cetylpyridinium Chloride (CPyCl) and Sodium Salicylate (NaSal). Nature Publishing Group UK 2020-04-02 /pmc/articles/PMC7118116/ /pubmed/32242060 http://dx.doi.org/10.1038/s41598-020-62628-1 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Vitali, Valerio
Nava, Giovanni
Zanchetta, Giuliano
Bragheri, Francesca
Crespi, Andrea
Osellame, Roberto
Bellini, Tommaso
Cristiani, Ilaria
Minzioni, Paolo
Integrated Optofluidic Chip for Oscillatory Microrheology
title Integrated Optofluidic Chip for Oscillatory Microrheology
title_full Integrated Optofluidic Chip for Oscillatory Microrheology
title_fullStr Integrated Optofluidic Chip for Oscillatory Microrheology
title_full_unstemmed Integrated Optofluidic Chip for Oscillatory Microrheology
title_short Integrated Optofluidic Chip for Oscillatory Microrheology
title_sort integrated optofluidic chip for oscillatory microrheology
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118116/
https://www.ncbi.nlm.nih.gov/pubmed/32242060
http://dx.doi.org/10.1038/s41598-020-62628-1
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