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Conditional down-regulation of GreA impacts expression of rRNA and transcription factors, affecting Mycobacterium smegmatis survival

Gre, one of the conserved transcription factors in bacteria, modulates RNA polymerase (RNAP) activity to ensure processivity and fidelity of RNA synthesis. Gre factors regulate transcription by inducing the intrinsic-endonucleolytic activity of RNAP, allowing the enzyme to resume transcription from...

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Detalles Bibliográficos
Autores principales: Jha, Rajiv Kumar, Udupa, Shubha, Rai, Ashutosh Kumar, Rani, Phoolwanti, Singh, Prakruti R., Govind, Shamitha, Nagaraja, Valakunja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118132/
https://www.ncbi.nlm.nih.gov/pubmed/32242064
http://dx.doi.org/10.1038/s41598-020-62703-7