Optimization of cell viability assays to improve replicability and reproducibility of cancer drug sensitivity screens

Cancer drug development has been riddled with high attrition rates, in part, due to poor reproducibility of preclinical models for drug discovery. Poor experimental design and lack of scientific transparency may cause experimental biases that in turn affect data quality, robustness and reproducibili...

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Detalles Bibliográficos
Autores principales: Larsson, Peter, Engqvist, Hanna, Biermann, Jana, Werner Rönnerman, Elisabeth, Forssell-Aronsson, Eva, Kovács, Anikó, Karlsson, Per, Helou, Khalil, Parris, Toshima Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118156/
https://www.ncbi.nlm.nih.gov/pubmed/32242081
http://dx.doi.org/10.1038/s41598-020-62848-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118156/
https://www.ncbi.nlm.nih.gov/pubmed/32242081
http://dx.doi.org/10.1038/s41598-020-62848-5

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