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Optimization of cell viability assays to improve replicability and reproducibility of cancer drug sensitivity screens
Cancer drug development has been riddled with high attrition rates, in part, due to poor reproducibility of preclinical models for drug discovery. Poor experimental design and lack of scientific transparency may cause experimental biases that in turn affect data quality, robustness and reproducibili...
Autores principales: | Larsson, Peter, Engqvist, Hanna, Biermann, Jana, Werner Rönnerman, Elisabeth, Forssell-Aronsson, Eva, Kovács, Anikó, Karlsson, Per, Helou, Khalil, Parris, Toshima Z. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118156/ https://www.ncbi.nlm.nih.gov/pubmed/32242081 http://dx.doi.org/10.1038/s41598-020-62848-5 |
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