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Modulating the Distant Spreading of Patient-Derived Colorectal Cancer Cells via Aspirin and Metformin
Although screening has reduced mortality rates for colorectal cancer (CRC), about 20% of patients still carry metastases at diagnosis. Postsurgery chemotherapy is toxic and induces drug resistance. Promising alternative strategies rely on repurposing drugs such as aspirin (ASA) and metformin (MET)....
Autores principales: | Palazzolo, Gemma, Mollica, Hilaria, Lusi, Valeria, Rutigliani, Mariangela, Di Francesco, Martina, Pereira, Rui Cruz, Filauro, Marco, Paleari, Laura, DeCensi, Andrea, Decuzzi, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118176/ https://www.ncbi.nlm.nih.gov/pubmed/32247264 http://dx.doi.org/10.1016/j.tranon.2020.100760 |
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