Cargando…
Recent progress in structural studies on TMEM16A channel
The calcium-activated chloride channel, also known as TMEM16A, shows both calcium and membrane potential dependent activation. The channel is expressed broadly and contributes to a variety of physiological processes, and it is expected to be a target for the treatment of diseases such as hypertensio...
Autores principales: | Shi, Sai, Pang, Chunli, Guo, Shuai, Chen, Yafei, Ma, Biao, Qu, Chang, Ji, Qiushuang, An, Hailong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118279/ https://www.ncbi.nlm.nih.gov/pubmed/32257055 http://dx.doi.org/10.1016/j.csbj.2020.03.015 |
Ejemplares similares
-
Identification of a druggable pocket of the calcium-activated chloride channel TMEM16A in its open state
por: Shi, Sai, et al.
Publicado: (2023) -
Theaflavin binds to a druggable pocket of TMEM16A channel and inhibits lung adenocarcinoma cell viability
por: Shi, Sai, et al.
Publicado: (2021) -
Zafirlukast inhibits the growth of lung adenocarcinoma via inhibiting TMEM16A channel activity
por: Shi, Sai, et al.
Publicado: (2022) -
Inhibition of TMEM16A by Natural Product Silibinin: Potential Lead Compounds for Treatment of Lung Adenocarcinoma
por: Guo, Shuai, et al.
Publicado: (2021) -
TMEM16A, a Homoharringtonine Receptor, as a Potential Endogenic Target for Lung Cancer Treatment
por: Guo, Shuai, et al.
Publicado: (2021)