Cargando…

Overexpression of Nrf2 promotes colon cancer progression via ERK and AKT signaling pathways

PURPOSE: We investigated the expression of Nrf2 in colorectal cancer and its correlation with clinicopathological characteristics as well as mechanisms and roles of Nrf2 expression including cell signaling pathway, survival, proliferation, and migration. METHODS: Nrf2 expression was measured in 12 a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Yoon Jin, Kim, Woo Il, Bae, Jin Ho, Cho, Moon Kyun, Lee, Sang Han, Nam, Hae Seon, Choi, In Ho, Cho, Sung Woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Surgical Society 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118325/ https://www.ncbi.nlm.nih.gov/pubmed/32274363 http://dx.doi.org/10.4174/astr.2020.98.4.159

Ejemplares similares

Cytohesin-2 Is Upregulated in Malignant Melanoma and Contributes to Tumor Growth
por: Lee, Yoon Jin, et al.
Publicado: (2019)

Cariporide Enhances the DNA Damage and Apoptosis in Acid-tolerable Malignant Mesothelioma H-2452 Cells
por: Lee, Yoon-Jin, et al.
Publicado: (2017)

Overexpression of KAI1 Protein in Diabetic Skin Tissues
por: Cho, Moon Kyun, et al.
Publicado: (2014)

Synergistic inhibition of mesothelioma cell growth by the combination of clofarabine and resveratrol involves Nrf2 downregulation
por: Lee, Yoon-Jin, et al.
Publicado: (2012)

Apigenin causes necroptosis by inducing ROS accumulation, mitochondrial dysfunction, and ATP depletion in malignant mesothelioma cells
por: Lee, Yoon-Jin, et al.
Publicado: (2020)

Incidental cholecystojejunal fistula treated with successful laparoscopic management
por: Jung, Hae Il, et al.
Publicado: (2014)

Expression of Nuclear Factor Erythroid 2 Protein in Malignant Cutaneous Tumors
por: Choi, Chang Yong, et al.
Publicado: (2014)

Simvastatin induces heme oxygenase-1 via NF-E2-related factor 2 (Nrf2) activation through ERK and PI3K/Akt pathway in colon cancer
por: Jang, Hyun Joo, et al.
Publicado: (2016)

Nrf2 Negatively Regulates Melanogenesis by Modulating PI3K/Akt Signaling
por: Shin, Jung-Min, et al.
Publicado: (2014)

Oxidative Damage and Nuclear Factor Erythroid 2-Related Factor 2 Protein Expression in Normal Skin and Keloid Tissue
por: Lee, Yoon Jin, et al.
Publicado: (2015)

Curcumin Enhances the Anticancer Effects of Binimetinib on Melanoma Cells by Inducing Mitochondrial Dysfunction and Cell Apoptosis with Necroptosis
por: Lee, Yoon Jin, et al.
Publicado: (2023)

A Case of Multiple Cutaneous Piloleiomyomas on the Neck
por: Lee, Yoon Jin, et al.
Publicado: (2018)

Abietane Diterpenoids Isolated from Torreya nucifera Disrupt Replication of Influenza Virus by Blocking the Phosphatidylinositol-3-Kinase (PI3K)-Akt and ERK Signaling Pathway
por: Bae, Jaehoon, et al.
Publicado: (2023)

Positron emission tomography detection of synchronous colon cancer in a patient with chronic lymphocytic leukemia
por: Lee, Jeong Eun, et al.
Publicado: (2013)

Concurrent induction of apoptosis and necroptosis in apigenin‑treated malignant mesothelioma cells: Reversal of Warburg effect through Akt inhibition and p53 upregulation
por: Lee, Yoon-Jin, et al.
Publicado: (2023)

Survey of experts on therapeutic policies and proposals for the optimal timing for allogeneic peripheral blood stem cell transplantation in transfusion-dependent patients with myelodysplastic syndrome-refractory anemia
por: Sohn, Sang Kyun, et al.
Publicado: (2016)

Dehydropeptidase 1 promotes metastasis through regulation of E-cadherin expression in colon cancer
por: Park, Sang Yoon, et al.
Publicado: (2016)

Astrocyte elevated gene-1 overexpression in hepatocellular carcinoma: an independent prognostic factor
por: Jung, Hae Il, et al.
Publicado: (2015)

Impact of Nrf2 overexpression on cholangiocarcinoma treatment and clinical prognosis
por: Lee, Huisong, et al.
Publicado: (2023)

Synergistic Renoprotective Effect of Melatonin and Zileuton by Inhibition of Ferroptosis via the AKT/mTOR/NRF2 Signaling in Kidney Injury and Fibrosis
por: Jung, Kyung Hee, et al.
Publicado: (2023)

Curative resection of leiomyosarcoma of the descending colon with metachronous liver metastasis: A case report
por: Lee, Soo-Hyeon, et al.
Publicado: (2023)

Galangin Activates the ERK/AKT-Driven Nrf2 Signaling Pathway to Increase the Level of Reduced Glutathione in Human Keratinocytes
por: Hewage, Susara Ruwan Kumara Madduma, et al.
Publicado: (2017)

Increased Production of α-Linolenic Acid in Soybean Seeds by Overexpression of Lesquerella FAD3-1
por: Yeom, Wan Woo, et al.
Publicado: (2020)

Poor glycemic control is associated with the risk of subclinical hypothyroidism in patients with type 2 diabetes mellitus
por: Cho, Jae Ho, et al.
Publicado: (2016)

Factors for Predicting Favorable Outcome of Percutaneous Epidural Adhesiolysis for Lumbar Disc Herniation
por: Moon, Sang Ho, et al.
Publicado: (2017)

Cep131 overexpression promotes centrosome amplification and colon cancer progression by regulating Plk4 stability
por: Kim, Dong Hyun, et al.
Publicado: (2019)

Eriodictyol Protects Endothelial Cells against Oxidative Stress-Induced Cell Death through Modulating ERK/Nrf2/ARE-Dependent Heme Oxygenase-1 Expression
por: Lee, Seung Eun, et al.
Publicado: (2015)

Effect of Activated Charcoal Fibers on the Survival of the House Dust Mite, Dermatophagoides pteronyssinus: A Pilot Study
por: Nam, Hae-Seon, et al.
Publicado: (2012)

FGFR4 Arg388 Is Correlated with Poor Survival in Resected Colon Cancer Promoting Epithelial to Mesenchymal Transition
por: Cho, Sang Hee, et al.
Publicado: (2017)

Dexamethasone Inhibits TGF-β1–Induced Cell Migration by Regulating the ERK and AKT Pathways in Human Colon Cancer Cells Via CYR61
por: Han, Sanghoon, et al.
Publicado: (2016)

Inhibition of ERK1/2 by silymarin in mouse mesangial cells
por: Youn, Cha Kyung, et al.
Publicado: (2017)

Colon perforation due to embolization coil for internal iliac aneurysm
por: Lee, Ho Kyun, et al.
Publicado: (2017)

Geriatric functional assessment for decision-making on adjuvant chemotherapy in older colon cancer patients
por: Bang, Hyun Jin, et al.
Publicado: (2022)

Fascaplysin Sensitizes Anti-Cancer Effects of Drugs Targeting AKT and AMPK
por: Oh, Taek-In, et al.
Publicado: (2017)

Overexpression of PD-L1 and PD-L2 Is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma
por: Jung, Hae Il, et al.
Publicado: (2017)

The effect of on-line hemodiafiltration on heart rate variability in end-stage renal disease
por: Park, Kyung Won, et al.
Publicado: (2013)

Cytoprotective effects of fermented oyster extracts against oxidative stress-induced DNA damage and apoptosis through activation of the Nrf2/HO-1 signaling pathway in MC3T3-E1 osteoblasts
por: Park, Cheol, et al.
Publicado: (2020)

Celecoxib-Induced Modulation of Colon Cancer CD133 Expression Occurs through AKT Inhibition and Is Monitored by (89)Zr Immuno-PET
por: Jung, Kyung-Ho, et al.
Publicado: (2022)

Chemotherapy adherence is a favorable prognostic factor for elderly patients with multiple myeloma who are treated with a frontline bortezomib-containing regimen
por: Cho, Hee-Jeong, et al.
Publicado: (2018)

The Role of digital subtraction angiography in the ventricular spot sign on the computed tomography angiography
por: Cho, Jun-Soo, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_slqp3d0rhd6ubr7pd4q9va51r8