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Physalin D inhibits RANKL-induced osteoclastogenesis and bone loss via regulating calcium signaling

We investigated the effects of physalin A, B, D, and F on osteoclastogenesis induced by receptor activator of nuclear factor kB ligand (RANKL). The biological functions of different physalins were first predicted using an in silico bioinformatic tool (BATMAN-TCM). Afterwards, we tested cell viabilit...

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Detalles Bibliográficos
Autores principales: Ding, Ning, Lu, Yanzhu, Cui, Hanmin, Ma, Qinyu, Qiu, Dongxia, Wei, Xueting, Dou, Ce, Cao, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118355/
https://www.ncbi.nlm.nih.gov/pubmed/31964464
http://dx.doi.org/10.5483/BMBRep.2020.53.3.147