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RNA Recognition and Cleavage by the SARS Coronavirus Endoribonuclease
The emerging disease SARS is caused by a novel coronavirus that encodes several unusual RNA-processing enzymes, including non-structural protein 15 (Nsp15), a hexameric endoribonuclease that preferentially cleaves at uridine residues.1., 2., 3. How Nsp15 recognizes and cleaves RNA is not well unders...
Autores principales: | Bhardwaj, Kanchan, Sun, Jingchuan, Holzenburg, Andreas, Guarino, Linda A., Kao, C. Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118729/ https://www.ncbi.nlm.nih.gov/pubmed/16828802 http://dx.doi.org/10.1016/j.jmb.2006.06.021 |
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