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author Meltzer, Eli O.
Hamilos, Daniel L.
Hadley, James A.
Lanza, Donald C.
Marple, Bradley F.
Nicklas, Richard A.
Bachert, Claus
Baraniuk, James
Baroody, Fuad M.
Benninger, Michael S.
Brook, Itzhak
Chowdhury, Badrul A.
Druce, Howard M.
Durham, Stephen
Ferguson, Berrylin
Gwaltney, Jack M.
Kaliner, Michael
Kennedy, David W.
Lund, Valerie
Naclerio, Robert
Pawankar, Ruby
Piccirillo, Jay F.
Rohane, Patricia
Simon, Ronald
Slavin, Raymond G.
Togias, Alkis
Wald, Ellen R.
Zinreich, S.James
author_facet Meltzer, Eli O.
Hamilos, Daniel L.
Hadley, James A.
Lanza, Donald C.
Marple, Bradley F.
Nicklas, Richard A.
Bachert, Claus
Baraniuk, James
Baroody, Fuad M.
Benninger, Michael S.
Brook, Itzhak
Chowdhury, Badrul A.
Druce, Howard M.
Durham, Stephen
Ferguson, Berrylin
Gwaltney, Jack M.
Kaliner, Michael
Kennedy, David W.
Lund, Valerie
Naclerio, Robert
Pawankar, Ruby
Piccirillo, Jay F.
Rohane, Patricia
Simon, Ronald
Slavin, Raymond G.
Togias, Alkis
Wald, Ellen R.
Zinreich, S.James
author_sort Meltzer, Eli O.
collection PubMed
description BACKGROUND: There is a need for more research on all forms of rhinosinusitis. Progress in this area has been hampered by a lack of consensus definitions and the limited number of published clinical trials. OBJECTIVES: To develop consensus definitions for rhinosinusitis and outline strategies useful in clinical trials. STUDY DESIGN: Five national societies, The American Academy of Allergy, Asthma and Immunology; The American Academy of Otolaryngic Allergy; The American Academy of Otolaryngology Head and Neck Surgery; The American College of Allergy, Asthma and Immunology; and the American Rhinologic Society formed an expert panel from multiple disciplines. Over two days, the panel developed definitions for rhinosinusitis and outlined strategies for design of clinical trials. RESULTS: Committee members agreed to adopt the term “rhinosinusitis” and reached consensus on definitions and strategies for clinical research on acute presumed bacterial rhinosinusitis, chronic rhinosinusitis without polyposis, chronic rhinosinusitis with polyposis, and classic allergic fungal rhinosinusitis. Symptom and objective criteria, measures for monitoring research progress, and use of symptom scoring tools, quality-of-life instruments, radiologic studies, and rhinoscopic assessment were outlined for each condition. CONCLUSIONS: The recommendations from this conference should improve accuracy of clinical diagnosis and serve as a starting point for design of rhinosinusitis clinical trials.
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spelling pubmed-71188602020-04-03 Rhinosinusitis: Establishing definitions for clinical research and patient care Meltzer, Eli O. Hamilos, Daniel L. Hadley, James A. Lanza, Donald C. Marple, Bradley F. Nicklas, Richard A. Bachert, Claus Baraniuk, James Baroody, Fuad M. Benninger, Michael S. Brook, Itzhak Chowdhury, Badrul A. Druce, Howard M. Durham, Stephen Ferguson, Berrylin Gwaltney, Jack M. Kaliner, Michael Kennedy, David W. Lund, Valerie Naclerio, Robert Pawankar, Ruby Piccirillo, Jay F. Rohane, Patricia Simon, Ronald Slavin, Raymond G. Togias, Alkis Wald, Ellen R. Zinreich, S.James Otolaryngol Head Neck Surg Article BACKGROUND: There is a need for more research on all forms of rhinosinusitis. Progress in this area has been hampered by a lack of consensus definitions and the limited number of published clinical trials. OBJECTIVES: To develop consensus definitions for rhinosinusitis and outline strategies useful in clinical trials. STUDY DESIGN: Five national societies, The American Academy of Allergy, Asthma and Immunology; The American Academy of Otolaryngic Allergy; The American Academy of Otolaryngology Head and Neck Surgery; The American College of Allergy, Asthma and Immunology; and the American Rhinologic Society formed an expert panel from multiple disciplines. Over two days, the panel developed definitions for rhinosinusitis and outlined strategies for design of clinical trials. RESULTS: Committee members agreed to adopt the term “rhinosinusitis” and reached consensus on definitions and strategies for clinical research on acute presumed bacterial rhinosinusitis, chronic rhinosinusitis without polyposis, chronic rhinosinusitis with polyposis, and classic allergic fungal rhinosinusitis. Symptom and objective criteria, measures for monitoring research progress, and use of symptom scoring tools, quality-of-life instruments, radiologic studies, and rhinoscopic assessment were outlined for each condition. CONCLUSIONS: The recommendations from this conference should improve accuracy of clinical diagnosis and serve as a starting point for design of rhinosinusitis clinical trials. American Academy of Allergy, Asthma and Immunology and by the American Academy of Otolaryngology-Head and Neck Surgery Foundation, Inc. Published by Mosby, Inc. 2004-12 2004-12-02 /pmc/articles/PMC7118860/ /pubmed/15577816 http://dx.doi.org/10.1016/j.otohns.2004.09.067 Text en Copyright © 2004 American Academy of Allergy, Asthma and Immunology and by the American Academy of Otolaryngology-Head and Neck Surgery Foundation, Inc. Published by Mosby, Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Meltzer, Eli O.
Hamilos, Daniel L.
Hadley, James A.
Lanza, Donald C.
Marple, Bradley F.
Nicklas, Richard A.
Bachert, Claus
Baraniuk, James
Baroody, Fuad M.
Benninger, Michael S.
Brook, Itzhak
Chowdhury, Badrul A.
Druce, Howard M.
Durham, Stephen
Ferguson, Berrylin
Gwaltney, Jack M.
Kaliner, Michael
Kennedy, David W.
Lund, Valerie
Naclerio, Robert
Pawankar, Ruby
Piccirillo, Jay F.
Rohane, Patricia
Simon, Ronald
Slavin, Raymond G.
Togias, Alkis
Wald, Ellen R.
Zinreich, S.James
Rhinosinusitis: Establishing definitions for clinical research and patient care
title Rhinosinusitis: Establishing definitions for clinical research and patient care
title_full Rhinosinusitis: Establishing definitions for clinical research and patient care
title_fullStr Rhinosinusitis: Establishing definitions for clinical research and patient care
title_full_unstemmed Rhinosinusitis: Establishing definitions for clinical research and patient care
title_short Rhinosinusitis: Establishing definitions for clinical research and patient care
title_sort rhinosinusitis: establishing definitions for clinical research and patient care
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118860/
https://www.ncbi.nlm.nih.gov/pubmed/15577816
http://dx.doi.org/10.1016/j.otohns.2004.09.067
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