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Challenges in the conduct of large simple trials of important generic questions in resource-poor settings: The CREATE and ECLA trial program evaluating GIK (glucose, insulin and potassium) and low-molecular-weight heparin in acute myocardial infarction()
BACKGROUND: Approximately 15.5 million deaths from cardiovascular diseases occur every year. About half are due to acute myocardial infarction (AMI), and 80% occur in low- and middle-income countries. Therefore, low-cost therapies would be invaluable. Although glucose-insulin-potassium (GIK) infusio...
Autores principales: | Yusuf, Salim, Mehta, Shamir R., Díaz, Rafael, Paolasso, Ernesto, Pais, Prem, Xavier, Denis, Xie, Changchun, Ahmed, Rashid J., Khazmi, Khawar, Zhu, Jun, Liu, Lisheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118878/ https://www.ncbi.nlm.nih.gov/pubmed/15632895 http://dx.doi.org/10.1016/j.ahj.2004.08.033 |
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