Live-attenuated bivalent measles virus-derived vaccines targeting Middle East respiratory syndrome coronavirus induce robust and multifunctional T cell responses against both viruses in an appropriate mouse model

Cases of Middle East respiratory syndrome coronavirus (MERS-CoV) continue to occur, making it one of the WHO´s targets for accelerated vaccine development. One vaccine candidate is based on live-attenuated measles virus (MV) vaccine encoding the MERS-CoV spike glycoprotein (MERS-S). MV(vac2)-MERS-S(...

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Detalles Bibliográficos
Autores principales: Bodmer, Bianca S., Fiedler, Anna H., Hanauer, Jan R.H., Prüfer, Steffen, Mühlebach, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118890/
https://www.ncbi.nlm.nih.gov/pubmed/29902727
http://dx.doi.org/10.1016/j.virol.2018.05.028

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