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MERS coronavirus nsp1 participates in an efficient propagation through a specific interaction with viral RNA
MERS-CoV is the only lethal human CoV still endemic in the Arabian Peninsula and neither vaccine nor therapeutics against MERS-CoV infection is available. The nsp1 of CoV is thought to be a major virulence factor because it suppresses protein synthesis through the degradation of host mRNA. In contra...
Autores principales: | Terada, Yutaka, Kawachi, Kengo, Matsuura, Yoshiharu, Kamitani, Wataru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118922/ https://www.ncbi.nlm.nih.gov/pubmed/28843094 http://dx.doi.org/10.1016/j.virol.2017.08.026 |
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