A novel virtual barcode strategy for accurate panel-wide variant calling in circulating tumor DNA

BACKGROUND: Hybrid capture-based next-generation sequencing of DNA has been widely applied in the detection of circulating tumor DNA (ctDNA). Various methods have been proposed for ctDNA detection, but low-allelic-fraction (AF) variants are still a great challenge. In addition, no panel-wide calling...

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Detalles Bibliográficos
Autores principales: Wu, Leilei, Deng, Qinfang, Xu, Ze, Zhou, Songwen, Li, Chao, Li, Yi-Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118954/
https://www.ncbi.nlm.nih.gov/pubmed/32245364
http://dx.doi.org/10.1186/s12859-020-3412-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118954/
https://www.ncbi.nlm.nih.gov/pubmed/32245364
http://dx.doi.org/10.1186/s12859-020-3412-2

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