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A novel virtual barcode strategy for accurate panel-wide variant calling in circulating tumor DNA
BACKGROUND: Hybrid capture-based next-generation sequencing of DNA has been widely applied in the detection of circulating tumor DNA (ctDNA). Various methods have been proposed for ctDNA detection, but low-allelic-fraction (AF) variants are still a great challenge. In addition, no panel-wide calling...
Autores principales: | Wu, Leilei, Deng, Qinfang, Xu, Ze, Zhou, Songwen, Li, Chao, Li, Yi-Xue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118954/ https://www.ncbi.nlm.nih.gov/pubmed/32245364 http://dx.doi.org/10.1186/s12859-020-3412-2 |
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