Bat-Origin Coronaviruses Expand Their Host Range to Pigs

Infections with bat-origin coronaviruses have caused severe illness in humans by ‘host jump’. Recently, novel bat-origin coronaviruses were found in pigs. The large number of mutations on the receptor-binding domain allowed the viruses to infect the new host, posing a potential threat to both agricu...

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Detalles Bibliográficos
Autores principales: Wang, Liang, Su, Shuo, Bi, Yuhai, Wong, Gary, Gao, George F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119057/
https://www.ncbi.nlm.nih.gov/pubmed/29680361
http://dx.doi.org/10.1016/j.tim.2018.03.001
Descripción
Sumario:Infections with bat-origin coronaviruses have caused severe illness in humans by ‘host jump’. Recently, novel bat-origin coronaviruses were found in pigs. The large number of mutations on the receptor-binding domain allowed the viruses to infect the new host, posing a potential threat to both agriculture and public health.

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