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Ross River virus envelope glycans contribute to disease through activation of the host complement system

Mannose binding lectin (MBL) generally plays a protective role during viral infection, yet MBL-mediated complement activation promotes Ross River virus (RRV)-induced inflammatory tissue destruction, contributing to arthritis and myositis. As MBL binds to carbohydrates, we hypothesized that N-linked...

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Detalles Bibliográficos
Autores principales:	Gunn, Bronwyn M., Jones, Jennifer E., Shabman, Reed S., Whitmore, Alan C., Sarkar, Sanjay, Blevins, Lance K., Morrison, Thomas E., Heise, Mark T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Published by Elsevier Inc. 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119116/ https://www.ncbi.nlm.nih.gov/pubmed/29324290 http://dx.doi.org/10.1016/j.virol.2017.12.022

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