PGRMC1 phosphorylation affects cell shape, motility, glycolysis, mitochondrial form and function, and tumor growth

BACKGROUND: Progesterone Receptor Membrane Component 1 (PGRMC1) is expressed in many cancer cells, where it is associated with detrimental patient outcomes. It contains phosphorylated tyrosines which evolutionarily preceded deuterostome gastrulation and tissue differentiation mechanisms. RESULTS: We...

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Detalles Bibliográficos
Autores principales: Thejer, Bashar M., Adhikary, Partho P., Kaur, Amandeep, Teakel, Sarah L., Van Oosterum, Ashleigh, Seth, Ishith, Pajic, Marina, Hannan, Katherine M., Pavy, Megan, Poh, Perlita, Jazayeri, Jalal A., Zaw, Thiri, Pascovici, Dana, Ludescher, Marina, Pawlak, Michael, Cassano, Juan C., Turnbull, Lynne, Jazayeri, Mitra, James, Alexander C., Coorey, Craig P., Roberts, Tara L., Kinder, Simon J., Hannan, Ross D., Patrick, Ellis, Molloy, Mark P., New, Elizabeth J., Fehm, Tanja N., Neubauer, Hans, Goldys, Ewa M., Weston, Leslie A., Cahill, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119165/
https://www.ncbi.nlm.nih.gov/pubmed/32245408
http://dx.doi.org/10.1186/s12860-020-00256-3

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