SCNrank: spectral clustering for network-based ranking to reveal potential drug targets and its application in pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is the most common pancreatic malignancy. Due to its wide heterogeneity, PDAC acts aggressively and responds poorly to most chemotherapies, causing an urgent need for the development of new therapeutic strategies. Cell lines have been used as the f...

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Detalles Bibliográficos
Autores principales: Liu, Enze, Zhang, Zhuang Zhuang, Cheng, Xiaolin, Liu, Xiaoqi, Cheng, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119297/
https://www.ncbi.nlm.nih.gov/pubmed/32241274
http://dx.doi.org/10.1186/s12920-020-0681-6

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