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Determination of microsomal lauric acid hydroxylase activity by HPLC with flow-through radiochemical quantitation

An assay for the microsomal hydroxylation of lauric acid (LA), based on HPLC with flow-through radiochemical detection, has been developed. Conditions were optimized for resolution and quantitation of three microsomal metabolites of LA, one of which has not been reported previously as a metabolite o...

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Detalles Bibliográficos
Autores principales: Romano, Maria C., Straub, Kenneth M., Yodis, Lee Ann P., Eckardt, Regina D., Newton, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119439/
https://www.ncbi.nlm.nih.gov/pubmed/3389520
http://dx.doi.org/10.1016/0003-2697(88)90093-0