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Progress of Research in Neonatal Sepsis
Neonatal sepsis remains a significant global problem with little progress made despite major efforts. At present, there is a lack of an accepted international consensus on the definition, diagnosis, and treatment of neonatal sepsis; the unclear understanding of the pathogenesis of neonatal sepsis le...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119971/ http://dx.doi.org/10.1007/978-981-13-3353-8_16 |
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author | Chen, Sheng Shi, Yuan |
author_facet | Chen, Sheng Shi, Yuan |
author_sort | Chen, Sheng |
collection | PubMed |
description | Neonatal sepsis remains a significant global problem with little progress made despite major efforts. At present, there is a lack of an accepted international consensus on the definition, diagnosis, and treatment of neonatal sepsis; the unclear understanding of the pathogenesis of neonatal sepsis leads to blindness in treatment, which will result in an unsatisfactory therapeutic outcome. In addition, some serious diseases caused by noninfectious factors, such as trauma, stress, asphyxia, and so on, have very similar pathophysiological results with neonatal sepsis. In this review we synthesize the recent advances in definition, incidence, causative agents, risk factors, pathophysiology, clinical manifestations, and diagnosis and treatment of neonatal sepsis. Of course, there are still many challenges to neonatal sepsis in many ways. |
format | Online Article Text |
id | pubmed-7119971 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
record_format | MEDLINE/PubMed |
spelling | pubmed-71199712020-04-06 Progress of Research in Neonatal Sepsis Chen, Sheng Shi, Yuan Severe Trauma and Sepsis Article Neonatal sepsis remains a significant global problem with little progress made despite major efforts. At present, there is a lack of an accepted international consensus on the definition, diagnosis, and treatment of neonatal sepsis; the unclear understanding of the pathogenesis of neonatal sepsis leads to blindness in treatment, which will result in an unsatisfactory therapeutic outcome. In addition, some serious diseases caused by noninfectious factors, such as trauma, stress, asphyxia, and so on, have very similar pathophysiological results with neonatal sepsis. In this review we synthesize the recent advances in definition, incidence, causative agents, risk factors, pathophysiology, clinical manifestations, and diagnosis and treatment of neonatal sepsis. Of course, there are still many challenges to neonatal sepsis in many ways. 2019-05-28 /pmc/articles/PMC7119971/ http://dx.doi.org/10.1007/978-981-13-3353-8_16 Text en © Springer Nature Singapore Pte Ltd. 2019 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Article Chen, Sheng Shi, Yuan Progress of Research in Neonatal Sepsis |
title | Progress of Research in Neonatal Sepsis |
title_full | Progress of Research in Neonatal Sepsis |
title_fullStr | Progress of Research in Neonatal Sepsis |
title_full_unstemmed | Progress of Research in Neonatal Sepsis |
title_short | Progress of Research in Neonatal Sepsis |
title_sort | progress of research in neonatal sepsis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119971/ http://dx.doi.org/10.1007/978-981-13-3353-8_16 |
work_keys_str_mv | AT chensheng progressofresearchinneonatalsepsis AT shiyuan progressofresearchinneonatalsepsis |