Viral Dynamics and Mathematical Models

Mathematical tools have been widely applied in understanding the dynamics and control of viral infections. Here we present some fundamental aspects of infection dynamics, starting with acute immunising infections as a case study for herd immunity and other important factors in the spread and control...

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Detalles Bibliográficos
Autores principales: Arinaminpathy, Nimalan, Metcalf, Charlotte Jessica E., Grenfell, Bryan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119994/
http://dx.doi.org/10.1007/978-1-4899-7448-8_5
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author Arinaminpathy, Nimalan
Metcalf, Charlotte Jessica E.
Grenfell, Bryan T.
author_facet Arinaminpathy, Nimalan
Metcalf, Charlotte Jessica E.
Grenfell, Bryan T.
author_sort Arinaminpathy, Nimalan
collection PubMed
description Mathematical tools have been widely applied in understanding the dynamics and control of viral infections. Here we present some fundamental aspects of infection dynamics, starting with acute immunising infections as a case study for herd immunity and other important factors in the spread and control of infection. We then discuss the dynamics of infections with more complex life histories, including chronic infections, and those showing evolution for immune escape. We conclude with a discussion of important gaps in our current understanding of viral dynamics, along with future research needs.
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spelling pubmed-71199942020-04-06 Viral Dynamics and Mathematical Models Arinaminpathy, Nimalan Metcalf, Charlotte Jessica E. Grenfell, Bryan T. Viral Infections of Humans Article Mathematical tools have been widely applied in understanding the dynamics and control of viral infections. Here we present some fundamental aspects of infection dynamics, starting with acute immunising infections as a case study for herd immunity and other important factors in the spread and control of infection. We then discuss the dynamics of infections with more complex life histories, including chronic infections, and those showing evolution for immune escape. We conclude with a discussion of important gaps in our current understanding of viral dynamics, along with future research needs. 2014-02-27 /pmc/articles/PMC7119994/ http://dx.doi.org/10.1007/978-1-4899-7448-8_5 Text en © Springer Science+Business Media New York 2014 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Arinaminpathy, Nimalan
Metcalf, Charlotte Jessica E.
Grenfell, Bryan T.
Viral Dynamics and Mathematical Models
title Viral Dynamics and Mathematical Models
title_full Viral Dynamics and Mathematical Models
title_fullStr Viral Dynamics and Mathematical Models
title_full_unstemmed Viral Dynamics and Mathematical Models
title_short Viral Dynamics and Mathematical Models
title_sort viral dynamics and mathematical models
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119994/
http://dx.doi.org/10.1007/978-1-4899-7448-8_5
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AT metcalfcharlottejessicae viraldynamicsandmathematicalmodels
AT grenfellbryant viraldynamicsandmathematicalmodels

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