Lung Transplantation and Precision Medicine

Lung transplantation is an accepted therapeutic option for end-stage lung diseases. Its history starts in the 1940s, initially hampered by early deaths due to perioperative problems and acute rejection. Improvement of surgical techniques and the introduction of immunosuppressive drugs resulted in lo...

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Autores principales: Beeckmans, Hanne, Saez, Berta, Van Herck, Anke, Sacreas, Annelore, Kaes, Janne, Heigl, Tobias, Vanstapel, Arno, Ordies, Sofie, Frick, Anna E., Verleden, Stijn E., Verleden, Geert M., Vos, Robin, Vanaudenaerde, Bart M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120453/
http://dx.doi.org/10.1007/978-3-030-31507-8_22
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author Beeckmans, Hanne
Saez, Berta
Van Herck, Anke
Sacreas, Annelore
Kaes, Janne
Heigl, Tobias
Vanstapel, Arno
Ordies, Sofie
Frick, Anna E.
Verleden, Stijn E.
Verleden, Geert M.
Vos, Robin
Vanaudenaerde, Bart M.
author_facet Beeckmans, Hanne
Saez, Berta
Van Herck, Anke
Sacreas, Annelore
Kaes, Janne
Heigl, Tobias
Vanstapel, Arno
Ordies, Sofie
Frick, Anna E.
Verleden, Stijn E.
Verleden, Geert M.
Vos, Robin
Vanaudenaerde, Bart M.
author_sort Beeckmans, Hanne
collection PubMed
description Lung transplantation is an accepted therapeutic option for end-stage lung diseases. Its history starts in the 1940s, initially hampered by early deaths due to perioperative problems and acute rejection. Improvement of surgical techniques and the introduction of immunosuppressive drugs resulted in longer survival. Chronic lung allograft dysfunction (CLAD), a new complication appeared and remains the most serious complication today. CLAD, the main reason why survival after lung transplantation is impaired compared to other solid-organ transplantations is characterized by a gradually increasing shortness of breath, reflected in a deterioration of pulmonary function status, respiratory insufficiency and possibly death.
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spelling pubmed-71204532020-04-06 Lung Transplantation and Precision Medicine Beeckmans, Hanne Saez, Berta Van Herck, Anke Sacreas, Annelore Kaes, Janne Heigl, Tobias Vanstapel, Arno Ordies, Sofie Frick, Anna E. Verleden, Stijn E. Verleden, Geert M. Vos, Robin Vanaudenaerde, Bart M. Precision in Pulmonary, Critical Care, and Sleep Medicine Article Lung transplantation is an accepted therapeutic option for end-stage lung diseases. Its history starts in the 1940s, initially hampered by early deaths due to perioperative problems and acute rejection. Improvement of surgical techniques and the introduction of immunosuppressive drugs resulted in longer survival. Chronic lung allograft dysfunction (CLAD), a new complication appeared and remains the most serious complication today. CLAD, the main reason why survival after lung transplantation is impaired compared to other solid-organ transplantations is characterized by a gradually increasing shortness of breath, reflected in a deterioration of pulmonary function status, respiratory insufficiency and possibly death. 2019-09-28 /pmc/articles/PMC7120453/ http://dx.doi.org/10.1007/978-3-030-31507-8_22 Text en © Springer Nature Switzerland AG 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Beeckmans, Hanne
Saez, Berta
Van Herck, Anke
Sacreas, Annelore
Kaes, Janne
Heigl, Tobias
Vanstapel, Arno
Ordies, Sofie
Frick, Anna E.
Verleden, Stijn E.
Verleden, Geert M.
Vos, Robin
Vanaudenaerde, Bart M.
Lung Transplantation and Precision Medicine
title Lung Transplantation and Precision Medicine
title_full Lung Transplantation and Precision Medicine
title_fullStr Lung Transplantation and Precision Medicine
title_full_unstemmed Lung Transplantation and Precision Medicine
title_short Lung Transplantation and Precision Medicine
title_sort lung transplantation and precision medicine
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120453/
http://dx.doi.org/10.1007/978-3-030-31507-8_22
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