Berberine Protects Against Simulated Ischemia/Reperfusion Injury-Induced H9C2 Cardiomyocytes Apoptosis In Vitro and Myocardial Ischemia/Reperfusion-Induced Apoptosis In Vivo by Regulating the Mitophagy-Mediated HIF-1α/BNIP3 Pathway

Berberine (BBR) has a variety of pharmacological activities and is widely used in Asian countries. However, the clinical application of BBR still lacks scientific basis, what protective mechanism of BBR against myocardial ischemia-reperfusion injury (MIRI). In vitro experiments, BBR pretreatment reg...

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Detalles Bibliográficos
Autores principales: Zhu, Na, Li, Jiang, Li, Yongli, Zhang, Yuwei, Du, Qiubo, Hao, Peiyuan, Li, Jinying, Cao, Xueming, Li, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120539/
https://www.ncbi.nlm.nih.gov/pubmed/32292345
http://dx.doi.org/10.3389/fphar.2020.00367

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