Adult-Onset Still’s Disease

Adult-onset Still’s disease (AOSD) is a rare systemic, autoinflammatory disorder that often presents in adolescence and early adulthood with fever, rash, and polyarthritis. There are significant genetic and clinical similarities with systemic juvenile idiopathic arthritis (sJIA) with a different chr...

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Detalles Bibliográficos
Autores principales: Efthimiou, Petros, Yadlapati, Sujani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120682/
http://dx.doi.org/10.1007/978-3-319-96929-9_19
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author Efthimiou, Petros
Yadlapati, Sujani
author_facet Efthimiou, Petros
Yadlapati, Sujani
author_sort Efthimiou, Petros
collection PubMed
description Adult-onset Still’s disease (AOSD) is a rare systemic, autoinflammatory disorder that often presents in adolescence and early adulthood with fever, rash, and polyarthritis. There are significant genetic and clinical similarities with systemic juvenile idiopathic arthritis (sJIA) with a different chronological disease onset. The disease can have many protean characteristics leading to delays in diagnosis. Treatment includes corticosteroids; traditional immunomodulators, such as methotrexate; and targeted biologic treatments that include IL-1 and IL-6 inhibitors.
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spelling pubmed-71206822020-04-06 Adult-Onset Still’s Disease Efthimiou, Petros Yadlapati, Sujani Auto-Inflammatory Syndromes Article Adult-onset Still’s disease (AOSD) is a rare systemic, autoinflammatory disorder that often presents in adolescence and early adulthood with fever, rash, and polyarthritis. There are significant genetic and clinical similarities with systemic juvenile idiopathic arthritis (sJIA) with a different chronological disease onset. The disease can have many protean characteristics leading to delays in diagnosis. Treatment includes corticosteroids; traditional immunomodulators, such as methotrexate; and targeted biologic treatments that include IL-1 and IL-6 inhibitors. 2018-07-14 /pmc/articles/PMC7120682/ http://dx.doi.org/10.1007/978-3-319-96929-9_19 Text en © Springer Nature Switzerland AG 2019 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Efthimiou, Petros
Yadlapati, Sujani
Adult-Onset Still’s Disease
title Adult-Onset Still’s Disease
title_full Adult-Onset Still’s Disease
title_fullStr Adult-Onset Still’s Disease
title_full_unstemmed Adult-Onset Still’s Disease
title_short Adult-Onset Still’s Disease
title_sort adult-onset still’s disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120682/
http://dx.doi.org/10.1007/978-3-319-96929-9_19
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