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Survivorship of Patellofemoral Osteochondral Allograft Transplantation

INTRODUCTION: We performed a survivorship analysis of patients treated with patellofemoral osteochondral allograft transplantation (OCA) using either a shell or plug technique and identified variables associated with graft failure. METHODS: Consecutive patients at two institutions who underwent OCA...

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Autores principales: Cotter, Eric J., Christian, David R., Frank, Rachel M., Abyar, Eildar, Wischmeier, Dillen, Yanke, Adam B., Farr, Jack, Cole, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120803/
https://www.ncbi.nlm.nih.gov/pubmed/32266337
http://dx.doi.org/10.1016/j.asmr.2019.06.003
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author Cotter, Eric J.
Christian, David R.
Frank, Rachel M.
Abyar, Eildar
Wischmeier, Dillen
Yanke, Adam B.
Farr, Jack
Cole, Brian J.
author_facet Cotter, Eric J.
Christian, David R.
Frank, Rachel M.
Abyar, Eildar
Wischmeier, Dillen
Yanke, Adam B.
Farr, Jack
Cole, Brian J.
author_sort Cotter, Eric J.
collection PubMed
description INTRODUCTION: We performed a survivorship analysis of patients treated with patellofemoral osteochondral allograft transplantation (OCA) using either a shell or plug technique and identified variables associated with graft failure. METHODS: Consecutive patients at two institutions who underwent OCA of the patellofemoral compartment between March 1, 2001 to March 1, 2015, were retrospectively identified at minimum 2 years' follow-up. Demographic information, intraoperative findings, and postoperative data were collected. Patients were divided into two groups on the basis of surgical technique (plug group and shell group). Failure was defined as revision OCA, conversion to arthroplasty, or gross appearance of graft degeneration on second-look arthroscopy. Logistic regression analysis was performed to identify patient- and surgery-specific variables associated with survivorship. RESULTS: Fifty patients were identified (36 women and 14 men; mean age 37.43 ± 8.87 years). Sixteen patients received plug allografts, whereas 34 received shell allografts. Forty percent of patients underwent a concomitant meniscal, ligamentous, malalignment, or chondral procedure. Five patients in the Plug Group (31.3%) underwent reoperation at a mean 1.37 ± 1.34 years, and 28 patients (82.4%) who received Shell OCA underwent reoperation at a mean 1.94 ± 1.92 years. Two patients in the plug group had graft failure at a mean 9.17 ± 0.93 years, whereas 13 patients in the shell group had graft failure at a mean 3.81 ± 2.78 years. Patients with plug allografts demonstrated 100% and 66% survival at 5 and 9.8 years, respectively. For the shell group, survivorship was 65.8% and 37% at 5 and 10.6 years, respectively. Increasing body mass index was associated with failure for the case series overall (odds ratio 1.33, P = .020). Traumatic cause was found to be protective of failure (odds ratio = 0.02, P = .035). CONCLUSIONS: Plug OCA of the patellofemoral compartment can be an efficacious procedure with quality mid-term outcomes. Shell OCA led to high failure rates at midterm outcomes. Increasing body mass index may predispose patients to failure, whereas traumatic cause of their lesion was associated with improved outcomes. LEVEL OF EVIDENCE: Level IV, Therapeutic case series.
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spelling pubmed-71208032020-04-07 Survivorship of Patellofemoral Osteochondral Allograft Transplantation Cotter, Eric J. Christian, David R. Frank, Rachel M. Abyar, Eildar Wischmeier, Dillen Yanke, Adam B. Farr, Jack Cole, Brian J. Arthrosc Sports Med Rehabil Original Article INTRODUCTION: We performed a survivorship analysis of patients treated with patellofemoral osteochondral allograft transplantation (OCA) using either a shell or plug technique and identified variables associated with graft failure. METHODS: Consecutive patients at two institutions who underwent OCA of the patellofemoral compartment between March 1, 2001 to March 1, 2015, were retrospectively identified at minimum 2 years' follow-up. Demographic information, intraoperative findings, and postoperative data were collected. Patients were divided into two groups on the basis of surgical technique (plug group and shell group). Failure was defined as revision OCA, conversion to arthroplasty, or gross appearance of graft degeneration on second-look arthroscopy. Logistic regression analysis was performed to identify patient- and surgery-specific variables associated with survivorship. RESULTS: Fifty patients were identified (36 women and 14 men; mean age 37.43 ± 8.87 years). Sixteen patients received plug allografts, whereas 34 received shell allografts. Forty percent of patients underwent a concomitant meniscal, ligamentous, malalignment, or chondral procedure. Five patients in the Plug Group (31.3%) underwent reoperation at a mean 1.37 ± 1.34 years, and 28 patients (82.4%) who received Shell OCA underwent reoperation at a mean 1.94 ± 1.92 years. Two patients in the plug group had graft failure at a mean 9.17 ± 0.93 years, whereas 13 patients in the shell group had graft failure at a mean 3.81 ± 2.78 years. Patients with plug allografts demonstrated 100% and 66% survival at 5 and 9.8 years, respectively. For the shell group, survivorship was 65.8% and 37% at 5 and 10.6 years, respectively. Increasing body mass index was associated with failure for the case series overall (odds ratio 1.33, P = .020). Traumatic cause was found to be protective of failure (odds ratio = 0.02, P = .035). CONCLUSIONS: Plug OCA of the patellofemoral compartment can be an efficacious procedure with quality mid-term outcomes. Shell OCA led to high failure rates at midterm outcomes. Increasing body mass index may predispose patients to failure, whereas traumatic cause of their lesion was associated with improved outcomes. LEVEL OF EVIDENCE: Level IV, Therapeutic case series. Elsevier 2019-09-26 /pmc/articles/PMC7120803/ /pubmed/32266337 http://dx.doi.org/10.1016/j.asmr.2019.06.003 Text en © 2019 Published by Elsevier on behalf of the Arthroscopy Association of North America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Cotter, Eric J.
Christian, David R.
Frank, Rachel M.
Abyar, Eildar
Wischmeier, Dillen
Yanke, Adam B.
Farr, Jack
Cole, Brian J.
Survivorship of Patellofemoral Osteochondral Allograft Transplantation
title Survivorship of Patellofemoral Osteochondral Allograft Transplantation
title_full Survivorship of Patellofemoral Osteochondral Allograft Transplantation
title_fullStr Survivorship of Patellofemoral Osteochondral Allograft Transplantation
title_full_unstemmed Survivorship of Patellofemoral Osteochondral Allograft Transplantation
title_short Survivorship of Patellofemoral Osteochondral Allograft Transplantation
title_sort survivorship of patellofemoral osteochondral allograft transplantation
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120803/
https://www.ncbi.nlm.nih.gov/pubmed/32266337
http://dx.doi.org/10.1016/j.asmr.2019.06.003
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