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Therapeutic and Medicinal Uses of Terpenes

Terpenes, also known as terpenoids are the largest and most diverse group of naturally occurring compounds. Based on the number of isoprene units they have, they are classified as mono, di, tri, tetra, and sesquiterpenes. They are mostly found in plants and form the major constituent of essential oi...

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Autores principales: Cox-Georgian, Destinney, Ramadoss, Niveditha, Dona, Chathu, Basu, Chhandak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120914/
http://dx.doi.org/10.1007/978-3-030-31269-5_15
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author Cox-Georgian, Destinney
Ramadoss, Niveditha
Dona, Chathu
Basu, Chhandak
author_facet Cox-Georgian, Destinney
Ramadoss, Niveditha
Dona, Chathu
Basu, Chhandak
author_sort Cox-Georgian, Destinney
collection PubMed
description Terpenes, also known as terpenoids are the largest and most diverse group of naturally occurring compounds. Based on the number of isoprene units they have, they are classified as mono, di, tri, tetra, and sesquiterpenes. They are mostly found in plants and form the major constituent of essential oils from plants. Among the natural products that provide medical benefits for an organism, terpenes play a major and variety of roles. The common plant sources of terpenes are tea, thyme, cannabis, Spanish sage, and citrus fruits (e.g., lemon, orange, mandarin). Terpenes have a wide range of medicinal uses among which antiplasmodial activity is notable as its mechanism of action is similar to the popular antimalarial drug in use—chloroquine. Monoterpenes specifically are widely studied for their antiviral property. With growing incidents of cancer and diabetes in modern world, terpenes also have the potential to serve as anticancer and antidiabetic reagents. Along with these properties, terpenes also allow for flexibility in route of administration and suppression of side effects. Certain terpenes were widely used in natural folk medicine. One such terpene is curcumin which holds anti-inflammatory, antioxidant, anticancer, antiseptic, antiplasmodial, astringent, digestive, diuretic, and many other properties. Curcumin has also become a recent trend in healthy foods and open doors for several medical researches. This chapter summarizes the various terpenes, their sources, medicinal properties, mechanism of action, and the recent studies that are underway for designing terpenes as a lead molecule in the modern medicine.
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spelling pubmed-71209142020-04-06 Therapeutic and Medicinal Uses of Terpenes Cox-Georgian, Destinney Ramadoss, Niveditha Dona, Chathu Basu, Chhandak Medicinal Plants Article Terpenes, also known as terpenoids are the largest and most diverse group of naturally occurring compounds. Based on the number of isoprene units they have, they are classified as mono, di, tri, tetra, and sesquiterpenes. They are mostly found in plants and form the major constituent of essential oils from plants. Among the natural products that provide medical benefits for an organism, terpenes play a major and variety of roles. The common plant sources of terpenes are tea, thyme, cannabis, Spanish sage, and citrus fruits (e.g., lemon, orange, mandarin). Terpenes have a wide range of medicinal uses among which antiplasmodial activity is notable as its mechanism of action is similar to the popular antimalarial drug in use—chloroquine. Monoterpenes specifically are widely studied for their antiviral property. With growing incidents of cancer and diabetes in modern world, terpenes also have the potential to serve as anticancer and antidiabetic reagents. Along with these properties, terpenes also allow for flexibility in route of administration and suppression of side effects. Certain terpenes were widely used in natural folk medicine. One such terpene is curcumin which holds anti-inflammatory, antioxidant, anticancer, antiseptic, antiplasmodial, astringent, digestive, diuretic, and many other properties. Curcumin has also become a recent trend in healthy foods and open doors for several medical researches. This chapter summarizes the various terpenes, their sources, medicinal properties, mechanism of action, and the recent studies that are underway for designing terpenes as a lead molecule in the modern medicine. 2019-11-12 /pmc/articles/PMC7120914/ http://dx.doi.org/10.1007/978-3-030-31269-5_15 Text en © Springer Nature Switzerland AG 2019 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Cox-Georgian, Destinney
Ramadoss, Niveditha
Dona, Chathu
Basu, Chhandak
Therapeutic and Medicinal Uses of Terpenes
title Therapeutic and Medicinal Uses of Terpenes
title_full Therapeutic and Medicinal Uses of Terpenes
title_fullStr Therapeutic and Medicinal Uses of Terpenes
title_full_unstemmed Therapeutic and Medicinal Uses of Terpenes
title_short Therapeutic and Medicinal Uses of Terpenes
title_sort therapeutic and medicinal uses of terpenes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120914/
http://dx.doi.org/10.1007/978-3-030-31269-5_15
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