Virus Evolution in the Face of the Host Response

Microbial infections are highly dynamic. Viruses have evolved two main strategies against the host response: interaction or evasion. Interaction is typical of complex DNA viruses. Their genomes encode a number of proteins that exert modulatory functions that alter the immune response of the host. Ev...

Descripción completa

Detalles Bibliográficos
Autor principal: Domingo, Esteban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120965/
http://dx.doi.org/10.1007/1-4020-3312-5_25
_version_ 1783515093386919936
author Domingo, Esteban
author_facet Domingo, Esteban
author_sort Domingo, Esteban
collection PubMed
description Microbial infections are highly dynamic. Viruses have evolved two main strategies against the host response: interaction or evasion. Interaction is typical of complex DNA viruses. Their genomes encode a number of proteins that exert modulatory functions that alter the immune response of the host. Evasion strategy is used mainly by RNA viruses, and is based on high mutation rates and quasispecies dynamics. The complexity of viral populations demands research on new antiviral strategies that take into consideration the adaptive potential of viruses, in particular RNA viruses.
format Online
Article
Text
id pubmed-7120965
institution National Center for Biotechnology Information
language English
publishDate 2005
record_format MEDLINE/PubMed
spelling pubmed-71209652020-04-06 Virus Evolution in the Face of the Host Response Domingo, Esteban Applications of Gene-Based Technologies for Improving Animal Production and Health in Developing Countries Article Microbial infections are highly dynamic. Viruses have evolved two main strategies against the host response: interaction or evasion. Interaction is typical of complex DNA viruses. Their genomes encode a number of proteins that exert modulatory functions that alter the immune response of the host. Evasion strategy is used mainly by RNA viruses, and is based on high mutation rates and quasispecies dynamics. The complexity of viral populations demands research on new antiviral strategies that take into consideration the adaptive potential of viruses, in particular RNA viruses. 2005 /pmc/articles/PMC7120965/ http://dx.doi.org/10.1007/1-4020-3312-5_25 Text en © IAEA 2005 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Domingo, Esteban
Virus Evolution in the Face of the Host Response
title Virus Evolution in the Face of the Host Response
title_full Virus Evolution in the Face of the Host Response
title_fullStr Virus Evolution in the Face of the Host Response
title_full_unstemmed Virus Evolution in the Face of the Host Response
title_short Virus Evolution in the Face of the Host Response
title_sort virus evolution in the face of the host response
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120965/
http://dx.doi.org/10.1007/1-4020-3312-5_25
work_keys_str_mv AT domingoesteban virusevolutioninthefaceofthehostresponse

Ejemplares similares