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Long Non-coding RNA
Rapid development in genome-wide transcriptional analyses has led to the discovery of a large number of non-coding transcripts, also called long non-coding RNA (lncRNA). LncRNAs harbor biological activities including regulation of protein-coding gene expression at epigenetic, transcriptional and pos...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121004/ http://dx.doi.org/10.1007/978-1-4939-3070-8_4 |
| _version_ | 1783515102652137472 |
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| author | Gullerova, Monika |
| author_facet | Gullerova, Monika |
| author_sort | Gullerova, Monika |
| collection | PubMed |
| description | Rapid development in genome-wide transcriptional analyses has led to the discovery of a large number of non-coding transcripts, also called long non-coding RNA (lncRNA). LncRNAs harbor biological activities including regulation of protein-coding gene expression at epigenetic, transcriptional and post-transcriptional levels. They also take a part in various physiological and pathological processes, participating in cell development, immunity, disease processes and oncogenesis. Here I discuss and summarize, current knowledge about lncRNA origin, function and involvement in human disease. |
| format | Online Article Text |
| id | pubmed-7121004 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2015 |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-71210042020-04-06 Long Non-coding RNA Gullerova, Monika Genomic Elements in Health, Disease and Evolution Article Rapid development in genome-wide transcriptional analyses has led to the discovery of a large number of non-coding transcripts, also called long non-coding RNA (lncRNA). LncRNAs harbor biological activities including regulation of protein-coding gene expression at epigenetic, transcriptional and post-transcriptional levels. They also take a part in various physiological and pathological processes, participating in cell development, immunity, disease processes and oncogenesis. Here I discuss and summarize, current knowledge about lncRNA origin, function and involvement in human disease. 2015-06-24 /pmc/articles/PMC7121004/ http://dx.doi.org/10.1007/978-1-4939-3070-8_4 Text en © Springer Science+Business Media New York 2015 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
| spellingShingle | Article Gullerova, Monika Long Non-coding RNA |
| title | Long Non-coding RNA |
| title_full | Long Non-coding RNA |
| title_fullStr | Long Non-coding RNA |
| title_full_unstemmed | Long Non-coding RNA |
| title_short | Long Non-coding RNA |
| title_sort | long non-coding rna |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121004/ http://dx.doi.org/10.1007/978-1-4939-3070-8_4 |
| work_keys_str_mv | AT gullerovamonika longnoncodingrna |