Efficacy, Safety and Targets in Topical and Transdermal Active and Excipient Delivery

A key requirement for topical and transdermal active delivery is the effective delivery of an active to a desired target site, to achieve both safe and efficacious outcomes. This chapter seeks to explore the importance of the pharmacological, toxicological and therapeutic properties of actives and e...

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Autores principales: Mohammed, Yousuf H., Moghimi, Hamid R., Yousef, Shereen A., Chandrasekaran, Navin C., Bibi, Césa R., Sukumar, Sinduja C., Grice, Jeffrey E., Sakran, Wedad, Roberts, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121119/
http://dx.doi.org/10.1007/978-3-662-53270-6_23
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author Mohammed, Yousuf H.
Moghimi, Hamid R.
Yousef, Shereen A.
Chandrasekaran, Navin C.
Bibi, Césa R.
Sukumar, Sinduja C.
Grice, Jeffrey E.
Sakran, Wedad
Roberts, Michael S.
author_facet Mohammed, Yousuf H.
Moghimi, Hamid R.
Yousef, Shereen A.
Chandrasekaran, Navin C.
Bibi, Césa R.
Sukumar, Sinduja C.
Grice, Jeffrey E.
Sakran, Wedad
Roberts, Michael S.
author_sort Mohammed, Yousuf H.
collection PubMed
description A key requirement for topical and transdermal active delivery is the effective delivery of an active to a desired target site, to achieve both safe and efficacious outcomes. This chapter seeks to explore the importance of the pharmacological, toxicological and therapeutic properties of actives and excipients, as well as the site of action as complementary components in percutaneous absorption. This is crucial for optimized topical and transdermal product design.
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spelling pubmed-71211192020-04-06 Efficacy, Safety and Targets in Topical and Transdermal Active and Excipient Delivery Mohammed, Yousuf H. Moghimi, Hamid R. Yousef, Shereen A. Chandrasekaran, Navin C. Bibi, Césa R. Sukumar, Sinduja C. Grice, Jeffrey E. Sakran, Wedad Roberts, Michael S. Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin Article A key requirement for topical and transdermal active delivery is the effective delivery of an active to a desired target site, to achieve both safe and efficacious outcomes. This chapter seeks to explore the importance of the pharmacological, toxicological and therapeutic properties of actives and excipients, as well as the site of action as complementary components in percutaneous absorption. This is crucial for optimized topical and transdermal product design. 2017-01-25 /pmc/articles/PMC7121119/ http://dx.doi.org/10.1007/978-3-662-53270-6_23 Text en © Springer-Verlag Berlin Heidelberg 2017 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Mohammed, Yousuf H.
Moghimi, Hamid R.
Yousef, Shereen A.
Chandrasekaran, Navin C.
Bibi, Césa R.
Sukumar, Sinduja C.
Grice, Jeffrey E.
Sakran, Wedad
Roberts, Michael S.
Efficacy, Safety and Targets in Topical and Transdermal Active and Excipient Delivery
title Efficacy, Safety and Targets in Topical and Transdermal Active and Excipient Delivery
title_full Efficacy, Safety and Targets in Topical and Transdermal Active and Excipient Delivery
title_fullStr Efficacy, Safety and Targets in Topical and Transdermal Active and Excipient Delivery
title_full_unstemmed Efficacy, Safety and Targets in Topical and Transdermal Active and Excipient Delivery
title_short Efficacy, Safety and Targets in Topical and Transdermal Active and Excipient Delivery
title_sort efficacy, safety and targets in topical and transdermal active and excipient delivery
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121119/
http://dx.doi.org/10.1007/978-3-662-53270-6_23
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