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Severe Sepsis and Septic Shock

This chapter reviews the remarkable recent advances in the understanding of the molecular basis that underlies the pathophysiology of sepsis. This knowledge has improved diagnostic techniques and introduced new therapeutic agents into the standard management of patients with severe sepsis/septic sho...

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Detalles Bibliográficos
Autor principal: Opal, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121326/
http://dx.doi.org/10.1007/978-0-387-68113-9_15
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author Opal, Steven M.
author_facet Opal, Steven M.
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description This chapter reviews the remarkable recent advances in the understanding of the molecular basis that underlies the pathophysiology of sepsis. This knowledge has improved diagnostic techniques and introduced new therapeutic agents into the standard management of patients with severe sepsis/septic shock. The current treatment regimens for sepsis are discussed, and the evidence to support each major treatment strategy is outlined in detail. Research priorities to further the optimal management of septic shock in the future are highlighted.
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spelling pubmed-71213262020-04-06 Severe Sepsis and Septic Shock Opal, Steven M. Surgery Article This chapter reviews the remarkable recent advances in the understanding of the molecular basis that underlies the pathophysiology of sepsis. This knowledge has improved diagnostic techniques and introduced new therapeutic agents into the standard management of patients with severe sepsis/septic shock. The current treatment regimens for sepsis are discussed, and the evidence to support each major treatment strategy is outlined in detail. Research priorities to further the optimal management of septic shock in the future are highlighted. 2008 /pmc/articles/PMC7121326/ http://dx.doi.org/10.1007/978-0-387-68113-9_15 Text en © Springer Science+Business Media, LLC 2008 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Opal, Steven M.
Severe Sepsis and Septic Shock
title Severe Sepsis and Septic Shock
title_full Severe Sepsis and Septic Shock
title_fullStr Severe Sepsis and Septic Shock
title_full_unstemmed Severe Sepsis and Septic Shock
title_short Severe Sepsis and Septic Shock
title_sort severe sepsis and septic shock
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121326/
http://dx.doi.org/10.1007/978-0-387-68113-9_15
work_keys_str_mv AT opalstevenm severesepsisandsepticshock