The Immune Epitope Database and Analysis Resource

Epitopes are defined as the molecular structures interacting with specific receptors of the immune system such as antibodies, MHC, and T cell receptor molecules. The Immune Epitope Database and Analysis Resource (IEDB, http://www.immuneepitope.org) is a database specifically devoted to immune epitop...

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Autores principales: Sette, A., Bui, H. H., Sidney, J., Bourne, P., Buus, S., Fleri, W., Kubo, R., Lund, O., Nemazee, D., Ponomarenko, J. V., Sathiamurthy, M., Stewart, S., Way, S., Wilson, S. S., Peters, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121516/
http://dx.doi.org/10.1007/11818564_14
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author Sette, A.
Bui, H. H.
Sidney, J.
Bourne, P.
Buus, S.
Fleri, W.
Kubo, R.
Lund, O.
Nemazee, D.
Ponomarenko, J. V.
Sathiamurthy, M.
Stewart, S.
Way, S.
Wilson, S. S.
Peters, B.
author_facet Sette, A.
Bui, H. H.
Sidney, J.
Bourne, P.
Buus, S.
Fleri, W.
Kubo, R.
Lund, O.
Nemazee, D.
Ponomarenko, J. V.
Sathiamurthy, M.
Stewart, S.
Way, S.
Wilson, S. S.
Peters, B.
author_sort Sette, A.
collection PubMed
description Epitopes are defined as the molecular structures interacting with specific receptors of the immune system such as antibodies, MHC, and T cell receptor molecules. The Immune Epitope Database and Analysis Resource (IEDB, http://www.immuneepitope.org) is a database specifically devoted to immune epitope data. The database is populated with intrinsic and context-dependent epitope data curated from the scientific literature by immunologists, biochemists, and microbiologists. An analysis resource is linked to the database which hosts various bioinformatics tools to analyze epitope data as well as to predict de novo epitopes. The availability of the IEDB will facilitate the exploration of immunity to infectious diseases, allergies, autoimmune diseases, and cancer. The utility of the IEDB was recently demonstrated through a comprehensive analysis of all current information regarding antibody and T cell epitopes derived from influenza A and determining possible cross-reactivity among H5N1 avian flu and human flu viruses.
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spelling pubmed-71215162020-04-06 The Immune Epitope Database and Analysis Resource Sette, A. Bui, H. H. Sidney, J. Bourne, P. Buus, S. Fleri, W. Kubo, R. Lund, O. Nemazee, D. Ponomarenko, J. V. Sathiamurthy, M. Stewart, S. Way, S. Wilson, S. S. Peters, B. Pattern Recognition in Bioinformatics Article Epitopes are defined as the molecular structures interacting with specific receptors of the immune system such as antibodies, MHC, and T cell receptor molecules. The Immune Epitope Database and Analysis Resource (IEDB, http://www.immuneepitope.org) is a database specifically devoted to immune epitope data. The database is populated with intrinsic and context-dependent epitope data curated from the scientific literature by immunologists, biochemists, and microbiologists. An analysis resource is linked to the database which hosts various bioinformatics tools to analyze epitope data as well as to predict de novo epitopes. The availability of the IEDB will facilitate the exploration of immunity to infectious diseases, allergies, autoimmune diseases, and cancer. The utility of the IEDB was recently demonstrated through a comprehensive analysis of all current information regarding antibody and T cell epitopes derived from influenza A and determining possible cross-reactivity among H5N1 avian flu and human flu viruses. 2006 /pmc/articles/PMC7121516/ http://dx.doi.org/10.1007/11818564_14 Text en © Springer-Verlag Berlin Heidelberg 2006 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Sette, A.
Bui, H. H.
Sidney, J.
Bourne, P.
Buus, S.
Fleri, W.
Kubo, R.
Lund, O.
Nemazee, D.
Ponomarenko, J. V.
Sathiamurthy, M.
Stewart, S.
Way, S.
Wilson, S. S.
Peters, B.
The Immune Epitope Database and Analysis Resource
title The Immune Epitope Database and Analysis Resource
title_full The Immune Epitope Database and Analysis Resource
title_fullStr The Immune Epitope Database and Analysis Resource
title_full_unstemmed The Immune Epitope Database and Analysis Resource
title_short The Immune Epitope Database and Analysis Resource
title_sort immune epitope database and analysis resource
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121516/
http://dx.doi.org/10.1007/11818564_14
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