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Origins of the regulated secretory pathway

Modes of transport of soluble (or luminal) secretory proteins synthesized in the endoplasmic reticulum (ER) could be divided into two groups. The socalled constitutive secretory pathway (CSP) is common to all eukaryotic cells, constantly delivering constitutive soluble secretory proteins (CSSPs) lin...

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Detalles Bibliográficos
Autores principales: Mironov, Alexander A., Arvan, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121582/
http://dx.doi.org/10.1007/978-3-211-76310-0_30
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author Mironov, Alexander A.
Arvan, Peter
author_facet Mironov, Alexander A.
Arvan, Peter
author_sort Mironov, Alexander A.
collection PubMed
description Modes of transport of soluble (or luminal) secretory proteins synthesized in the endoplasmic reticulum (ER) could be divided into two groups. The socalled constitutive secretory pathway (CSP) is common to all eukaryotic cells, constantly delivering constitutive soluble secretory proteins (CSSPs) linked to the rate of protein synthesis but largely independent of external stimuli. In regulated secretion, protein is sorted from the Golgi into storage/secretory granules (SGs) whose contents are released when stimuli trigger their final fusion with the plasma membrane (Hannah et al. 1999).
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spelling pubmed-71215822020-04-06 Origins of the regulated secretory pathway Mironov, Alexander A. Arvan, Peter The Golgi Apparatus Article Modes of transport of soluble (or luminal) secretory proteins synthesized in the endoplasmic reticulum (ER) could be divided into two groups. The socalled constitutive secretory pathway (CSP) is common to all eukaryotic cells, constantly delivering constitutive soluble secretory proteins (CSSPs) linked to the rate of protein synthesis but largely independent of external stimuli. In regulated secretion, protein is sorted from the Golgi into storage/secretory granules (SGs) whose contents are released when stimuli trigger their final fusion with the plasma membrane (Hannah et al. 1999). 2008 /pmc/articles/PMC7121582/ http://dx.doi.org/10.1007/978-3-211-76310-0_30 Text en © Springer-Verlag/Wien 2008 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Mironov, Alexander A.
Arvan, Peter
Origins of the regulated secretory pathway
title Origins of the regulated secretory pathway
title_full Origins of the regulated secretory pathway
title_fullStr Origins of the regulated secretory pathway
title_full_unstemmed Origins of the regulated secretory pathway
title_short Origins of the regulated secretory pathway
title_sort origins of the regulated secretory pathway
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121582/
http://dx.doi.org/10.1007/978-3-211-76310-0_30
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