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The Neutrophil

The neutrophil provides a crucial defence against fungal infections. This numerous phagocyte is recruited rapidly to sites of infection, where it detects pathogens through a range of pathogen-recognition receptors. Phagocytosis and the generation of a range of microbicidal molecules neutralises the...

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Detalles Bibliográficos
Autores principales: Dockrell, David H., McGrath, Emmet E., Whyte, Moria K.B., Sabroe, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122062/
http://dx.doi.org/10.1007/1-4020-5492-0_3
Descripción
Sumario:The neutrophil provides a crucial defence against fungal infections. This numerous phagocyte is recruited rapidly to sites of infection, where it detects pathogens through a range of pathogen-recognition receptors. Phagocytosis and the generation of a range of microbicidal molecules neutralises the pathogen, following which neutrophil death by apoptosis triggers an injury-limiting resolution process facilitating the restoration of normal tissue architecture