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Characteristics of Microbes Most Likely to Cause Pandemics and Global Catastrophes

Predicting which pathogen will confer the highest global catastrophic biological risk (GCBR) of a pandemic is a difficult task. Many approaches are retrospective and premised on prior pandemics; however, such an approach may fail to appreciate novel threats that do not have exact historical preceden...

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Detalles Bibliográficos
Autores principales: Adalja, Amesh A., Watson, Matthew, Toner, Eric S., Cicero, Anita, Inglesby, Thomas V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122301/
https://www.ncbi.nlm.nih.gov/pubmed/31463536
http://dx.doi.org/10.1007/82_2019_176
Descripción
Sumario:Predicting which pathogen will confer the highest global catastrophic biological risk (GCBR) of a pandemic is a difficult task. Many approaches are retrospective and premised on prior pandemics; however, such an approach may fail to appreciate novel threats that do not have exact historical precedent. In this paper, based on a study and project we undertook, a new paradigm for pandemic preparedness is presented. This paradigm seeks to root pandemic risk in actual attributes possessed by specific classes of microbial organisms and leads to specific recommendations to augment preparedness activities.