Self-Replicating RNA

Self-replicating RNA derived from the genomes of positive strand RNA viruses represents a powerful tool for both molecular studies on virus biology and approaches to novel safe and effective vaccines. The following chapter summarizes the principles how such RNAs can be established and used for desig...

Descripción completa

Detalles Bibliográficos
Autores principales: Tews, Birke Andrea, Meyers, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122455/
https://www.ncbi.nlm.nih.gov/pubmed/27987141
http://dx.doi.org/10.1007/978-1-4939-6481-9_2
_version_ 1783515421895294976
author Tews, Birke Andrea
Meyers, Gregor
author_facet Tews, Birke Andrea
Meyers, Gregor
author_sort Tews, Birke Andrea
collection PubMed
description Self-replicating RNA derived from the genomes of positive strand RNA viruses represents a powerful tool for both molecular studies on virus biology and approaches to novel safe and effective vaccines. The following chapter summarizes the principles how such RNAs can be established and used for design of vaccines. Due to the large variety of strategies needed to circumvent specific pitfalls in the design of such constructs the technical details of the experiments are not described here but can be found in the cited literature.
format Online
Article
Text
id pubmed-7122455
institution National Center for Biotechnology Information
language English
publishDate 2016
record_format MEDLINE/PubMed
spelling pubmed-71224552020-04-06 Self-Replicating RNA Tews, Birke Andrea Meyers, Gregor RNA Vaccines Article Self-replicating RNA derived from the genomes of positive strand RNA viruses represents a powerful tool for both molecular studies on virus biology and approaches to novel safe and effective vaccines. The following chapter summarizes the principles how such RNAs can be established and used for design of vaccines. Due to the large variety of strategies needed to circumvent specific pitfalls in the design of such constructs the technical details of the experiments are not described here but can be found in the cited literature. 2016-06-11 /pmc/articles/PMC7122455/ /pubmed/27987141 http://dx.doi.org/10.1007/978-1-4939-6481-9_2 Text en © Springer Science+Business Media New York 2017 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Tews, Birke Andrea
Meyers, Gregor
Self-Replicating RNA
title Self-Replicating RNA
title_full Self-Replicating RNA
title_fullStr Self-Replicating RNA
title_full_unstemmed Self-Replicating RNA
title_short Self-Replicating RNA
title_sort self-replicating rna
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122455/
https://www.ncbi.nlm.nih.gov/pubmed/27987141
http://dx.doi.org/10.1007/978-1-4939-6481-9_2
work_keys_str_mv AT tewsbirkeandrea selfreplicatingrna
AT meyersgregor selfreplicatingrna

Ejemplares similares