Cargando…

Fever Management in Intensive Care Patients with Infections

Fever is one of the cardinal signs of infection and, nearly 120 years after William Osler’s statement in his address to the 47(th) annual meeting of the American Medical Association [1], infectious diseases remain a major cause of morbidity and mortality. Despite this, it is unclear whether fever it...

Descripción completa

Detalles Bibliográficos
Autores principales: Young, P., Saxena, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122612/
http://dx.doi.org/10.1007/978-3-319-03746-2_1
_version_ 1783515456590577664
author Young, P.
Saxena, M.
author_facet Young, P.
Saxena, M.
author_sort Young, P.
collection PubMed
description Fever is one of the cardinal signs of infection and, nearly 120 years after William Osler’s statement in his address to the 47(th) annual meeting of the American Medical Association [1], infectious diseases remain a major cause of morbidity and mortality. Despite this, it is unclear whether fever itself is truly the enemy or whether, in fact, the febrile response represents an important means to help the body fight infection. Furthermore, it is unclear whether the administration of antipyretic medications or physical cooling measures to patients with fever and infection is beneficial or harmful [2, 3]. Here, we review the biology of fever, the significance of the febrile response in animals and humans, and the current evidence-base regarding the utility of treating fever in intensive care patients with infectious diseases.
format Online
Article
Text
id pubmed-7122612
institution National Center for Biotechnology Information
language English
publishDate 2014
record_format MEDLINE/PubMed
spelling pubmed-71226122020-04-06 Fever Management in Intensive Care Patients with Infections Young, P. Saxena, M. Annual Update in Intensive Care and Emergency Medicine 2014 Article Fever is one of the cardinal signs of infection and, nearly 120 years after William Osler’s statement in his address to the 47(th) annual meeting of the American Medical Association [1], infectious diseases remain a major cause of morbidity and mortality. Despite this, it is unclear whether fever itself is truly the enemy or whether, in fact, the febrile response represents an important means to help the body fight infection. Furthermore, it is unclear whether the administration of antipyretic medications or physical cooling measures to patients with fever and infection is beneficial or harmful [2, 3]. Here, we review the biology of fever, the significance of the febrile response in animals and humans, and the current evidence-base regarding the utility of treating fever in intensive care patients with infectious diseases. 2014 /pmc/articles/PMC7122612/ http://dx.doi.org/10.1007/978-3-319-03746-2_1 Text en © Springer International Publishing Switzerland and BioMed Central Ltd. 2014 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Young, P.
Saxena, M.
Fever Management in Intensive Care Patients with Infections
title Fever Management in Intensive Care Patients with Infections
title_full Fever Management in Intensive Care Patients with Infections
title_fullStr Fever Management in Intensive Care Patients with Infections
title_full_unstemmed Fever Management in Intensive Care Patients with Infections
title_short Fever Management in Intensive Care Patients with Infections
title_sort fever management in intensive care patients with infections
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122612/
http://dx.doi.org/10.1007/978-3-319-03746-2_1
work_keys_str_mv AT youngp fevermanagementinintensivecarepatientswithinfections
AT saxenam fevermanagementinintensivecarepatientswithinfections