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Murine lupus is neutrophil elastase-independent in the MRL.Fas(lpr) model
Loss of tolerance to nuclear antigens and multisystem tissue destruction is a hallmark of systemic lupus erythematosus (SLE). Although the source of autoantigen in lupus remains elusive, a compelling hypothetical source is dead cell debris that drives autoimmune activation. Prior reports suggest tha...
Autores principales: | Gordon, Rachael A., Tilstra, Jeremy S., Marinov, Anthony, Nickerson, Kevin M., Bastacky, Sheldon I., Shlomchik, Mark J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122749/ https://www.ncbi.nlm.nih.gov/pubmed/32243431 http://dx.doi.org/10.1371/journal.pone.0226396 |
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