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Murine lupus is neutrophil elastase-independent in the MRL.Fas(lpr) model

Loss of tolerance to nuclear antigens and multisystem tissue destruction is a hallmark of systemic lupus erythematosus (SLE). Although the source of autoantigen in lupus remains elusive, a compelling hypothetical source is dead cell debris that drives autoimmune activation. Prior reports suggest tha...

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Detalles Bibliográficos
Autores principales: Gordon, Rachael A., Tilstra, Jeremy S., Marinov, Anthony, Nickerson, Kevin M., Bastacky, Sheldon I., Shlomchik, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122749/
https://www.ncbi.nlm.nih.gov/pubmed/32243431
http://dx.doi.org/10.1371/journal.pone.0226396

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