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Global Stability Analysis of HIV+ Model

We developed and studied a mathematical model of HIV+. Two equilibriums points were found, disease free and endemic equilibrium, and basic reproduction ratio [Formula: see text] was also calculated by the use of next generation matrix. Global stability analysis of the equilibria was carried out by t...

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Autores principales: Saad, Farouk Tijjani, Sanlidag, Tamer, Hincal, Evren, Sayan, Murat, Baba, Isa Abdullahi, Kaymakamzade, Bilgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122938/
http://dx.doi.org/10.1007/978-3-030-04164-9_109
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author Saad, Farouk Tijjani
Sanlidag, Tamer
Hincal, Evren
Sayan, Murat
Baba, Isa Abdullahi
Kaymakamzade, Bilgen
author_facet Saad, Farouk Tijjani
Sanlidag, Tamer
Hincal, Evren
Sayan, Murat
Baba, Isa Abdullahi
Kaymakamzade, Bilgen
author_sort Saad, Farouk Tijjani
collection PubMed
description We developed and studied a mathematical model of HIV+. Two equilibriums points were found, disease free and endemic equilibrium, and basic reproduction ratio [Formula: see text] was also calculated by the use of next generation matrix. Global stability analysis of the equilibria was carried out by the use of Lyapunov function, and it was shown that the stability of the equilibria depends on the magnitude of the basic reproduction ratio. When [Formula: see text] , the disease free equilibrium is globally asymptotically stable, and disease dies out. On the other hand if [Formula: see text] , the endemic equilibrium is globally asymptotically stable and epidemics occurs. Reported cases of 13646 HIV-1 positive were obtained in the year 2016 from Ministry of Health, Turkey (MOH). This data is used to present the numerical simulations, which supports the analytic result. [Formula: see text] was found to be 1.98998, which is bigger than 1, this shows the threat posed by HIV in Turkey.
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spelling pubmed-71229382020-04-06 Global Stability Analysis of HIV+ Model Saad, Farouk Tijjani Sanlidag, Tamer Hincal, Evren Sayan, Murat Baba, Isa Abdullahi Kaymakamzade, Bilgen 13th International Conference on Theory and Application of Fuzzy Systems and Soft Computing — ICAFS-2018 Article We developed and studied a mathematical model of HIV+. Two equilibriums points were found, disease free and endemic equilibrium, and basic reproduction ratio [Formula: see text] was also calculated by the use of next generation matrix. Global stability analysis of the equilibria was carried out by the use of Lyapunov function, and it was shown that the stability of the equilibria depends on the magnitude of the basic reproduction ratio. When [Formula: see text] , the disease free equilibrium is globally asymptotically stable, and disease dies out. On the other hand if [Formula: see text] , the endemic equilibrium is globally asymptotically stable and epidemics occurs. Reported cases of 13646 HIV-1 positive were obtained in the year 2016 from Ministry of Health, Turkey (MOH). This data is used to present the numerical simulations, which supports the analytic result. [Formula: see text] was found to be 1.98998, which is bigger than 1, this shows the threat posed by HIV in Turkey. 2018-12-29 /pmc/articles/PMC7122938/ http://dx.doi.org/10.1007/978-3-030-04164-9_109 Text en © Springer Nature Switzerland AG 2019 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Saad, Farouk Tijjani
Sanlidag, Tamer
Hincal, Evren
Sayan, Murat
Baba, Isa Abdullahi
Kaymakamzade, Bilgen
Global Stability Analysis of HIV+ Model
title Global Stability Analysis of HIV+ Model
title_full Global Stability Analysis of HIV+ Model
title_fullStr Global Stability Analysis of HIV+ Model
title_full_unstemmed Global Stability Analysis of HIV+ Model
title_short Global Stability Analysis of HIV+ Model
title_sort global stability analysis of hiv+ model
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122938/
http://dx.doi.org/10.1007/978-3-030-04164-9_109
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