Development of High-Throughput Fluorescent-Based Screens to Accelerate Discovery of P2X Inhibitors from Animal Venoms

[Image: see text] Animal venoms can play an important role in drug discovery, as they are a rich source of evolutionarily tuned compounds that target a variety of ion channels and receptors. To date, there are six FDA-approved drugs derived from animal venoms, with recent work using high-throughput...

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Detalles Bibliográficos
Autores principales: Bibic, Lucka, Herzig, Volker, King, Glenn F., Stokes, Leanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7123434/
https://www.ncbi.nlm.nih.gov/pubmed/31532206
http://dx.doi.org/10.1021/acs.jnatprod.9b00410

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