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How Immune Complexes from Certain IgG NAbs and Any F(ab′)(2) Can Mediate Excessive Complement Activation
In sepsis death follows an excessive inflammatory response involving cytokines and complement that is activated primarily via the amplifying C3/C5 convertase. Excessive stimulation of complement amplification requires IgG-containing or F(ab′)(2)-containing immune complexes (IC) that capture dimeric...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7123756/ https://www.ncbi.nlm.nih.gov/pubmed/22903675 http://dx.doi.org/10.1007/978-1-4614-3461-0_14 |