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To clear or to fear: An innate perspective on factor VIII immunity

The enigma that is factor VIII immunogenicity remains ever pertinent in the treatment of hemophilia A. Development of neutralizing antibodies against the therapeutic protein in 25–30% of patients likely depends on the appropriate activation of the innate immune response shortly following antigen enc...

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Detalles Bibliográficos
Autores principales: Lai, Jesse Derek, Georgescu, Maria Teofana, Hough, Christine, Lillicrap, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124272/
https://www.ncbi.nlm.nih.gov/pubmed/26547364
http://dx.doi.org/10.1016/j.cellimm.2015.10.011

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