Targeting mir128-3p alleviates myocardial insulin resistance and prevents ischemia-induced heart failure

Myocardial insulin resistance contributes to heart failure in response to pathological stresses, therefore, a therapeutic strategy to maintain cardiac insulin pathways requires further investigation. We demonstrated that insulin receptor substrate 1 (IRS1) was reduced in failing mouse hearts post-my...

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Detalles Bibliográficos
Autores principales: Ruiz-Velasco, Andrea, Zi, Min, Hille, Susanne S, Azam, Tayyiba, Kaur, Namrita, Jiang, Juwei, Nguyen, Binh, Sekeres, Karolina, Binder, Pablo, Collins, Lucy, Pu, Fay, Xiao, Han, Guan, Kaomei, Frey, Norbert, Cartwright, Elizabeth J, Müller, Oliver J, Wang, Xin, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124275/
https://www.ncbi.nlm.nih.gov/pubmed/32223896
http://dx.doi.org/10.7554/eLife.54298

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