Implementation of the cobas Liat influenza point-of-care test into an emergency department during a high-incidence season: a retrospective evaluation following real-world implementation

The cobas Liat influenza A/B and respiratory syncytial virus (RSV) assay (Liat) was used in the adult emergency department of a large London hospital from 21(st) January 2018 to 14(th) April 2018. Influenza was detected in 308 of 1027 (30%) samples tested; influenza A in 157 (15.3%), influenza B in...

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Autores principales: Youngs, J., Iqbal, Y., Glass, S., Riley, P., Pope, C., Planche, T., Carrington, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd on behalf of The Healthcare Infection Society. 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124296/
https://www.ncbi.nlm.nih.gov/pubmed/30562558
http://dx.doi.org/10.1016/j.jhin.2018.12.008
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author Youngs, J.
Iqbal, Y.
Glass, S.
Riley, P.
Pope, C.
Planche, T.
Carrington, D.
author_facet Youngs, J.
Iqbal, Y.
Glass, S.
Riley, P.
Pope, C.
Planche, T.
Carrington, D.
author_sort Youngs, J.
collection PubMed
description The cobas Liat influenza A/B and respiratory syncytial virus (RSV) assay (Liat) was used in the adult emergency department of a large London hospital from 21(st) January 2018 to 14(th) April 2018. Influenza was detected in 308 of 1027 (30%) samples tested; influenza A in 157 (15.3%), influenza B in 149 (14.5%) and RSV in 28 (2.7%). When compared against Fast Track Diagnostics Respiratory Pathogens 21 multiplex polymerase chain reaction and Cepheid Xpert Xpress Flu/RSV assay, Liat performance for the detection of influenza A or B was: sensitivity 85% [95% confidence interval (CI) 76–92)], specificity 98% (95% CI 97–99), negative predictive value 94% (95% CI 92–96) and positive predictive value 95% (95% CI 91–97).
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spelling pubmed-71242962020-04-08 Implementation of the cobas Liat influenza point-of-care test into an emergency department during a high-incidence season: a retrospective evaluation following real-world implementation Youngs, J. Iqbal, Y. Glass, S. Riley, P. Pope, C. Planche, T. Carrington, D. J Hosp Infect Article The cobas Liat influenza A/B and respiratory syncytial virus (RSV) assay (Liat) was used in the adult emergency department of a large London hospital from 21(st) January 2018 to 14(th) April 2018. Influenza was detected in 308 of 1027 (30%) samples tested; influenza A in 157 (15.3%), influenza B in 149 (14.5%) and RSV in 28 (2.7%). When compared against Fast Track Diagnostics Respiratory Pathogens 21 multiplex polymerase chain reaction and Cepheid Xpert Xpress Flu/RSV assay, Liat performance for the detection of influenza A or B was: sensitivity 85% [95% confidence interval (CI) 76–92)], specificity 98% (95% CI 97–99), negative predictive value 94% (95% CI 92–96) and positive predictive value 95% (95% CI 91–97). Published by Elsevier Ltd on behalf of The Healthcare Infection Society. 2019-03 2018-12-16 /pmc/articles/PMC7124296/ /pubmed/30562558 http://dx.doi.org/10.1016/j.jhin.2018.12.008 Text en © 2018 Published by Elsevier Ltd on behalf of The Healthcare Infection Society. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Youngs, J.
Iqbal, Y.
Glass, S.
Riley, P.
Pope, C.
Planche, T.
Carrington, D.
Implementation of the cobas Liat influenza point-of-care test into an emergency department during a high-incidence season: a retrospective evaluation following real-world implementation
title Implementation of the cobas Liat influenza point-of-care test into an emergency department during a high-incidence season: a retrospective evaluation following real-world implementation
title_full Implementation of the cobas Liat influenza point-of-care test into an emergency department during a high-incidence season: a retrospective evaluation following real-world implementation
title_fullStr Implementation of the cobas Liat influenza point-of-care test into an emergency department during a high-incidence season: a retrospective evaluation following real-world implementation
title_full_unstemmed Implementation of the cobas Liat influenza point-of-care test into an emergency department during a high-incidence season: a retrospective evaluation following real-world implementation
title_short Implementation of the cobas Liat influenza point-of-care test into an emergency department during a high-incidence season: a retrospective evaluation following real-world implementation
title_sort implementation of the cobas liat influenza point-of-care test into an emergency department during a high-incidence season: a retrospective evaluation following real-world implementation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124296/
https://www.ncbi.nlm.nih.gov/pubmed/30562558
http://dx.doi.org/10.1016/j.jhin.2018.12.008
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