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Large-scale Identification of N-linked Intact Glycopeptides in Human Serum using HILIC Enrichment and Spectral Library Search

Large-scale identification of N-linked intact glycopeptides by liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) in human serum is challenging because of the wide dynamic range of serum protein abundances, the lack of a complete serum N-glycan database and the existence of prote...

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Detalles Bibliográficos
Autores principales: Shu, Qingbo, Li, Mengjie, Shu, Lian, An, Zhiwu, Wang, Jifeng, Lv, Hao, Yang, Ming, Cai, Tanxi, Hu, Tony, Fu, Yan, Yang, Fuquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124471/
https://www.ncbi.nlm.nih.gov/pubmed/32102970
http://dx.doi.org/10.1074/mcp.RA119.001791