Cargando…

Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9

Protein phosphorylation cascades play a central role in the regulation of cell growth and protein kinases PKA, Sch9 and Ypk1 take center stage in regulating this process in S. cerevisiae. To understand how these kinases co-ordinately regulate cellular functions we compared the phospho-proteome of ex...

Descripción completa

Detalles Bibliográficos
Autores principales:	Plank, Michael, Perepelkina, Mariya, Müller, Markus, Vaga, Stefania, Zou, Xiaoming, Bourgoint, Clélia, Berti, Marina, Saarbach, Jacques, Haesendonckx, Steven, Winssinger, Nicolas, Aebersold, Ruedi, Loewith, Robbie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Biochemistry and Molecular Biology 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124472/ https://www.ncbi.nlm.nih.gov/pubmed/32102971 http://dx.doi.org/10.1074/mcp.RA120.001955

Ejemplares similares

The AGC Kinase YpkA Regulates Sphingolipids Biosynthesis and Physically Interacts With SakA MAP Kinase in Aspergillus fumigatus
por: Fabri, João Henrique Tadini Marilhano, et al.
Publicado: (2019)

TORC1 Promotes Phosphorylation of Ribosomal Protein S6 via the AGC Kinase Ypk3 in Saccharomyces cerevisiae
por: González, Asier, et al.
Publicado: (2015)

The Stress-Sensing TORC2 Complex Activates Yeast AGC-Family Protein Kinase Ypk1 at Multiple Novel Sites
por: Leskoske, Kristin L., et al.
Publicado: (2017)

AGC/AKT Protein Kinase SCH9 Is Critical to Pathogenic Development and Overwintering Survival in Magnaporthe oryzae
por: Batool, Wajjiha, et al.
Publicado: (2022)

Plasma membrane proteins Slm1 and Slm2 mediate activation of the AGC kinase Ypk1 by TORC2 and sphingolipids in S. cerevisiae
por: Niles, Brad J., et al.
Publicado: (2012)

Kinase-templated abiotic reaction
por: Saarbach, J., et al.
Publicado: (2017)

Target of rapamycin complex 2–dependent phosphorylation of the coat protein Pan1 by Akl1 controls endocytosis dynamics in Saccharomyces cerevisiae
por: Bourgoint, Clélia, et al.
Publicado: (2018)

The AGC Kinase SsAgc1 Regulates Sporisorium scitamineum Mating/Filamentation and Pathogenicity
por: Wang, Yixu, et al.
Publicado: (2019)

The conserved Pkh–Ypk kinase cascade is required for endocytosis in yeast
por: deHart, Amy K.A., et al.
Publicado: (2002)

TORC2 controls endocytosis through plasma membrane tension
por: Riggi, Margot, et al.
Publicado: (2019)

Identification of a Covalent Importin-5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides
por: Liu, Weilong, et al.
Publicado: (2021)

The wheat AGC kinase TaAGC1 is a positive contributor to host resistance to the necrotrophic pathogen Rhizoctonia cerealis
por: Zhu, Xiuliang, et al.
Publicado: (2015)

Functional Characterization of Aspergillus nidulans ypkA, a Homologue of the Mammalian Kinase SGK
por: Colabardini, Ana Cristina, et al.
Publicado: (2013)

The Ypk1 protein kinase signaling pathway is rewired and not essential for viability in Candida albicans
por: Ramírez-Zavala, Bernardo, et al.
Publicado: (2023)

Uncoupling TORC2 from AGC kinases inhibits tumour growth
por: Cameron, Angus J.M., et al.
Publicado: (2017)

AGC family kinase 1 participates in trogocytosis but not in phagocytosis in Entamoeba histolytica
por: Somlata, et al.
Publicado: (2017)

SPARK regulates AGC kinases central to the Toxoplasma gondii asexual cycle
por: Herneisen, Alice L., et al.
Publicado: (2023)

Evolutionary Adaptations of Plant AGC Kinases: From Light Signaling to Cell Polarity Regulation
por: Rademacher, Eike H., et al.
Publicado: (2012)

The AGC Kinase Inhibitor H89 Attenuates Airway Inflammation in Mouse Models of Asthma
por: Reber, Laurent L., et al.
Publicado: (2012)

STAT3 enhances the constitutive activity of AGC kinases in melanoma by transactivating PDK1
por: Picco, María Elisa, et al.
Publicado: (2019)

TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids
por: Muir, Alexander, et al.
Publicado: (2014)

Phosphorylation of the amino-terminus of the AGC kinase Gad8 prevents its interaction with TORC2
por: Du, Wei, et al.
Publicado: (2016)

The AGC protein kinase UNICORN controls planar growth by attenuating PDK1 in Arabidopsis thaliana
por: Scholz, Sebastian, et al.
Publicado: (2019)

EGOC inhibits TOROID polymerization by structurally activating TORC1
por: Prouteau, Manoël, et al.
Publicado: (2023)

Ultrastructure expansion microscopy reveals the cellular architecture of budding and fission yeast
por: Hinterndorfer, Kerstin, et al.
Publicado: (2022)

TORC1 Organised in Inhibited Domains (TOROIDs) regulate TORC1 activity
por: Prouteau, Manoël, et al.
Publicado: (2017)

TORC2 and the AGC kinase Gad8 regulate phosphorylation of the ribosomal protein S6 in fission yeast
por: Du, Wei, et al.
Publicado: (2012)

Phosphorylation of the TOR ATP binding domain by AGC kinase constitutes a novel mode of TOR inhibition
por: Hálová, Lenka, et al.
Publicado: (2013)

Correction: The AGC protein kinase UNICORN controls planar growth by attenuating PDK1 in Arabidopsis thaliana
por: Scholz, Sebastian, et al.
Publicado: (2019)

Metabolomic changes of the multi (-AGC-) kinase inhibitor AT13148 in cells, mice and patients are associated with NOS regulation
por: Pal, Akos, et al.
Publicado: (2020)

Genome-Wide Identification of the AGC Protein Kinase Gene Family Related to Photosynthesis in Rice (Oryza sativa)
por: Jiang, Yifei, et al.
Publicado: (2022)

Pkh1p-Ypk1p and Pkh1p-Sch9p Pathways Are Activated by Acetic Acid to Induce a Mitochondrial-Dependent Regulated Cell Death
por: Rego, António, et al.
Publicado: (2020)

Tricalbin-Mediated Contact Sites Control ER Curvature to Maintain Plasma Membrane Integrity
por: Collado, Javier, et al.
Publicado: (2019)

Interpretation and management of AGC cytology
por: Vasiliu, Cristina, et al.
Publicado: (2014)

GPR68 Contributes to Persistent Acidosis-Induced Activation of AGC Kinases and Tyrosine Phosphorylation in Organotypic Hippocampal Slices
por: Zhou, Guokun, et al.
Publicado: (2021)

AGC kinases and MAB4/MEL proteins maintain PIN polarity by limiting lateral diffusion in plant cells
por: Glanc, Matouš, et al.
Publicado: (2021)

The AGC kinase serum- and glucocorticoid-regulated kinase 1 (SGK1) regulates T(H)1 and T(H)2 differentiation downstream of mTORC2
por: Heikamp, Emily B., et al.
Publicado: (2014)

The Sch9 Kinase Regulates Conidium Size, Stress Responses, and Pathogenesis in Fusarium graminearum
por: Chen, Daipeng, et al.
Publicado: (2014)

The protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae
por: Swinnen, Erwin, et al.
Publicado: (2014)

Distinct regulation of Maf1 for lifespan extension by Protein kinase A and Sch9
por: Cai, Ying, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_4emnnco21sv0gocspd2veps1vr